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Zebrafish embryo cells need no receptors to receive signals from afar

Thin cellular protrusions called cytonemes can transport ligand–receptor complexes from a signal-producing cell to a receiving cell in the developing zebrafish embryo. Even cells lacking the receptor can be activated by this signalling system.

This is a summary of: Zhang, C. et al. Cytoneme-mediated transport of active Wnt5b–Ror2 complexes in zebrafish. Nature https://doi.org/10.1038/s41586-023-06850-7 (2023).

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doi: https://doi.org/10.1038/d41586-023-03659-2

‘Expert opinion’ and the figure are published under a CC BY 4.0 licence.

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