Abstract
An experimental model of quinine induced blindness is presented. Electrophysiological, angiographical and morphological examinations were made. The occurrence of blindness and any recovery from blindness was dependent upon the dose of quinine taken. As no evidence of acute retinal ischaemia was found it is concluded that quinine is retinotoxic.
Similar content being viewed by others
Article PDF
References
Zahn JR, Brinton GF, Norton E : Ocular quinine toxicity followed by electroretinogram, electro-oculogram, and pattern visually evoked potential. Am J Optometry & Phy Optics 1981, 58: 492–8.
Cibis GW, Burian HM, Blodi FC : Electroretinogram changes in acute quinine poisoning. Arch Ophthalmol 1973, 90: 307–9.
Thomas D : Forced acid diuresis and stellate ganglion block in the treatment of quinine poisoning. Anaesthesia 1984, 39: 257–60.
Browne GF and Coppel DL : Management of quinine overdose. Human Toxicol 1984, 3: 399–402.
Author information
Authors and Affiliations
Additional information
Presented at the Annual Congress of the Ophthalmological Society of the United Kingdom, April 1987.
Rights and permissions
About this article
Cite this article
Buchanan, T., Lyness, R., Collins, A. et al. An experimental study of quinine blindness. Eye 1, 522–524 (1987). https://doi.org/10.1038/eye.1987.78
Issue Date:
DOI: https://doi.org/10.1038/eye.1987.78