Abstract
Objective:
To compare the symptomatology of pregnant women with suspected listeriosis to culture confirmed listeriosis.
Study Design:
All cases of suspected and culture confirmed pregnancy-associated listeriosis from a single center were retrospectively reviewed assessing demographics, clinical, laboratory and pathological findings, and maternal, fetal and neonatal outcomes.
Results:
Listeriosis was identified in seven patients, none of whom belonged to the 117 women with suspected listeriosis. Women with confirmed infection were more likely to exhibit fever (P=0.01), flu-like symptoms (P=0.006), threatened preterm labor (P=0.05) and inflammatory markers (P=0.02), but less likely to exhibit gastrointestinal complaints (P=0.004) in comparison with suspected non-confirmed cases. Confirmed cases resulted in preterm delivery (n=5) and stillbirth (n=2). Neonatal complications included meningitis, respiratory disease and sepsis. Maternal outcomes were favorable.
Conclusion:
Although ‘febrile gastroenteritis’ is a poor predictor of listeriosis in pregnancy, fever, premature contractions and inflammatory markers are important risk indices prompting workup and adequate empiric treatment.
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Fouks, Y., Amit, S., Many, A. et al. Listeriosis in pregnancy: under-diagnosis despite over-treatment. J Perinatol 38, 26–30 (2018). https://doi.org/10.1038/jp.2017.145
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DOI: https://doi.org/10.1038/jp.2017.145
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