Nat. Immunol. 18, 832–842 (2017); published online 19 July 2017; corrected after print 17 August 2017

In the version of this article initially published, the final sentence of the third paragraph of the first subsection ('Monogenic periodic fever syndromes') incorrectly states that “Colchicine causes microtubule destabilization, thereby facilitating pyrin-inflammasome activation independently of RhoA.” That sentence should read: “Colchicine also causes microtubule destabilization, thereby inhibiting pyrin-inflammasome activation independently of RhoA.” The error has been corrected in the HTML and PDF versions of the article.