α-Synuclein is present at high levels in all neurons and their synapses. We now learn that this protein helps dilate the fusion pore, which forms transiently during vesicle exocytosis, promoting release of certain neurotransmitters.
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Selkoe, D. Showing transmitters the door: synucleins accelerate vesicle release. Nat Neurosci 20, 629–631 (2017). https://doi.org/10.1038/nn.4551
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DOI: https://doi.org/10.1038/nn.4551