Abstract
A new porous membrane was prepared from a block copolymer consisting of hydrophilic polyamide as outer segments and polyoxyethylene as an inner segment by casting the solution of the mixture of the block copolymer with polyoxyethylene glycol and drying up at room temperature, followed by immersing and rinsing in water. In the solute rejection test for some proteins, the concentration of the permeate was found to be much higher than that in the feed. Such peculiar condensation was much dependent not only upon the casting conditions for the porous membrane, but also upon permeation conditions such as the pressure difference, mechanical stirring, and the initial concentration of protein solutions. The present transport system is presumed to result from the delicate combination of the rapid adsorption of proteins onto the porous membrane and their transport driven by the lower pressure.
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Hashimoto, K., Sumitomo, H. & Yamamori, H. Novel Condensation System for Aqueous Solutions of Proteins. Facilitated Permeation of Proteins through a Porous Membrane Prepared from a Block Copolymer Consisting of Hydrophilic Polyamide and Polyoxyethylene Segments. Polym J 19, 1139–1145 (1987). https://doi.org/10.1295/polymj.19.1139
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DOI: https://doi.org/10.1295/polymj.19.1139