Abstract
This study has aimed at exploring the relationship between redox polymer structures and the electron transfer reaction from glucose oxidase (GOx) to an electrode via the redox polymers. Two series of flexible redox copolymers; poly[vinylferrocene-co-α-methacryloyl-ω-methoxy-oligo(ethylene oxide)] (VFc-MEO) and poly(vinylferrocene-co-dodecyl methacrylate) (VFc-MD), were prepared, where VFc and MD are hydrophobic monomers, while MEO is a hydrophilic monomer. These redox copolymers were utilized as electron mediators for the enzymatic reaction of GOx in carbon paste electrodes. Both of the flexible VFc-MEO and VFc-MD copolymers were found to function as polymeric mediators for the electron transfer reaction between GOx and the electrode, while the catalytic current responses were completely different depending on the structure of the polymeric mediators. The magnitude of the catalytic current of the VFc-MEO electrodes was larger than that of the VFc-MD electrodes at any VFc composition in the copolymers. At a constant glucose concentration, the catalytic current of the VFc-MEO electrodes passed through a maximum with increasing the VFc composition in the copolymers, whereas that of the VFc-MD electrodes monotonously increased with increasing the VFc composition. These differences in the electron transfer reaction have been explained in terms of the difference in amphiphilicity of the copolymers.
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Saito, T., Watanabe, M. Electron Transfer Reaction from Glucose Oxidase to an Electrode via Redox Copolymers. Polym J 31, 1149–1154 (1999). https://doi.org/10.1295/polymj.31.1149
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DOI: https://doi.org/10.1295/polymj.31.1149