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Design and function of smart biomembrane nanohybrids for biomedical applications: review

Polymer Journal volume 53, pages 587–592 (2021)Cite this article

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Abstract

Biological membranes that tailor their morphology to environmental stimuli are nature’s ultimate smart molecular systems. This focused review describes the design and function of smart biomembrane nanohybrids. Specifically, liposomes and exosomes can be functionalized with inorganic substances and polymers to afford hybridized artificial cell membranes. These membranes have a tailorable morphology and can incorporate functional integral membrane proteins.

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Acknowledgements

This work was financially supported by a Grant-in Aid from the Japan Society for the Promotion of Science (JSPS) KAKENHI Grant Number JP16H03842 (YS). We thank KA for kind support and Dr. Shinichi Sawada and Dr. Sada-atsu Mukai for their contributions. We thank Michael Scott Long from the Edanz Group (https://en-author-services.edanzgroup.com/ac) for editing a draft of this manuscript.

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  1. Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto, 615-8510, Japan

    Yoshihiro Sasaki & Kazunari Akiyoshi

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  1. Yoshihiro Sasaki
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  2. Kazunari Akiyoshi
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Correspondence to Yoshihiro Sasaki.

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Sasaki, Y., Akiyoshi, K. Design and function of smart biomembrane nanohybrids for biomedical applications: review. Polym J 53, 587–592 (2021). https://doi.org/10.1038/s41428-020-00453-z

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