Correction to: The Journal of Antibiotics (1992) 45, 1553–1556. https://doi.org/10.7164/antibiotics.45.1553

The authors of the above article misjudged the structure determination of MCF (metacytofilin). Our recent analyses using X-ray crystallography and NMR techniques revealed the correct structure as shown in Figs. 1, 2, and 3. The structure of MCF was identified with diatretol [1].

Fig. 1
figure 1

Structure of metacytofilin (MCF)

Fig. 2
figure 2

Deuterium isotope effects on 13C chemical shifts of MCF observed in CD3OD and CD3OH solutions

Fig. 3
figure 3

Molecular structure of MCF using SHELXT

Single-crystal X-ray data were collected on a Rigaku R-AXIS RAPID diffractometer using filtered Cu–Ka radiation. The crystal data are: empirical formula: C16H22N2O4, FW 306.36, crystal color: colorless, habit: platelet, crystal dimensions: 0.300 × 0.200 × 0.030 mm, crystal system: monoclinic, lattice type: primitive, lattice parameters: a = 6.06079 (14) Å, b = 17.1982 (4) Å, c = 9.1651 (2) Å, β = 108.523 (8)°, V = 905.83 (6) Å3, space group: P21, Z value: 2, D calc: 1.123 g/cm3, F 000: 328.00, µ (CuKa): 6.671 cm−1. The structure was solved by direct methods [2] and expanded using Fourier techniques. The non-hydrogen atoms were refined anisotropically. Hydrogen atoms were refined using the riding model. The final cycle of full-matrix least-squares refinement [3] on F2 was based on 3233 observed reflections and 199 variable parameters and converged (largest parameter shift was 0.00 times its esd) with unweighted and weighted agreement factors of:

$$R_1=S\Vert{\rm{Fo}}\vert \!-\!\vert{\rm{Fc}}\Vert/ S \vert{\rm{Fo}}\vert=0.0576,$$
$${{wR{_2}}} = \left[ {{{S}}\left( {{{w}}\left( {{\mathrm{Fo}}^2 - {\mathrm{Fc}}^2} \right)^2} \right){{/Sw}}\left( {{\mathrm{Fo}}^2} \right)^2} \right]^{1/2} = 0.1455.$$