The Early Manifest Glaucoma Trial (EMGT) showed that early reduction of intraocular pressure in patients newly diagnosed with primary open angle glaucoma using laser trabeculoplasty and topical betaxolol hydrochloride lowered the risk of disease progression. IOP intraocular pressure, NNT number needed to treat, POAG primary open angle glaucoma.
Reference to original study: Heijl A, Leske MC, Bengtsson B, Hyman L, Bengtsson B, Hussein M et al. Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial. Arch Ophthalmol. 2002; 120(10): 1268–1279.
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Di Croce, V., Wickramaratne, N., Henein, C. et al. Infographic of the Early Manifest Glaucoma Trial (EMGT). Eye 35, 2076 (2021). https://doi.org/10.1038/s41433-020-01371-3
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DOI: https://doi.org/10.1038/s41433-020-01371-3
