Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Sucrose transporters

SUC1’s mode of low-affinity transport

The new structure for the H+-coupled sucrose uptake transporter AtSUC1 helps us understand the mechanism used by plants for cellular sucrose uptake and phloem loading.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Riesmeier, J. W., Willmitzer, L. & Frommer, W. B. Isolation and characterization of a sucrose carrier cDNA from spinach by functional expression in yeast. EMBO J 11, 4705–4713 (1992).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Sauer, N. & Stolz, J. SUC1 and SUC2: two sucrose transporters from Arabidopsis thaliana; expression and characterization in baker’s yeast and identification of the histidine-tagged protein. Plant J 6, 67–77 (1994).

    Article  CAS  PubMed  Google Scholar 

  3. Bavnhøj, L. et al. Structure and sucrose binding mechanism of the plant SUC1 sucrose transporter. Nature Plants https://doi.org/10.1038/s41477-023-01421-0 (2023).

    Article  PubMed  Google Scholar 

  4. Reinders, A., Sivitz, A. B. & Ward, J. M. Evolution of plant sucrose uptake transporters (SUTs). Front. Plant Sci. 3, 00022 (2012).

    Article  CAS  Google Scholar 

  5. Sivitz, A. B., Reinders, A. & Ward, J. M. Arabidopsis sucrose transporter AtSUC1 is important for pollen germination and sucrose-induced anthocyanin accumulation. Plant Physiol 147, 92–100, https://doi.org/10.1104/pp.108.118992 (2008). pp.108.118992 [pii].

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Lasin, P., Weise, A., Reinders, A. & Ward, J. M. Arabidopsis Sucrose Transporter AtSuc1 introns act as strong enhancers of expression. Plant and Cell Physiol 61, 1054–1063 (2020).

    Article  CAS  Google Scholar 

  7. Sun, Y., Lin, Z., Reinders, A. & Ward, J. M. Functionally important amino acids in rice sucrose transporter OsSUT1. Biochemistry 51, 3284–3291 (2012).

    Article  CAS  PubMed  Google Scholar 

  8. Hitz, W. D., Card, P. J. & Ripp, K. G. Substrate recognition by a sucrose transporting protein. J Biol Chem 261, 11986–11991 (1986).

    Article  CAS  PubMed  Google Scholar 

  9. Chandran, D., Reinders, A. & Ward, J. M. Substrate specificity of the Arabidopsis thaliana sucrose transporter AtSUC2. J Biol Chem 278, 44320–44325, https://doi.org/10.1074/jbc.M308490200 (2003). M308490200 [pii].

    Article  CAS  PubMed  Google Scholar 

  10. Boorer, K. J., Loo, D. D., Frommer, W. B. & Wright, E. M. Transport mechanism of the cloned potato H+/sucrose cotransporter StSUT1. J Biol Chem 271, 25139–25144 (1996).

    Article  CAS  PubMed  Google Scholar 

  11. Sivitz, A. B., Reinders, A. & Ward, J. M. Analysis of the transport activity of barley sucrose transporter HvSUT1. Plant Cell Physiol 46, 1666–1673, https://doi.org/10.1093/pcp/pci182 (2005). pci182 [pii].

    Article  CAS  PubMed  Google Scholar 

  12. Reinders, A., Sun, Y., Karvonen, K. L. & Ward, J. M. Identification of amino acids important for substrate specificity in sucrose transporters using gene shuffling. J Biol Chem 287, 30296–30304, https://doi.org/10.1074/jbc.M112.372888 (2012). M112.372888 [pii].

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Sivitz, A. B. et al. Arabidopsis sucrose transporter AtSUC9. High-affinity transport activity, intragenic control of expression, and early flowering mutant phenotype. Plant Physiol 143, 188–198, https://doi.org/10.1104/pp.106.089003 (2007). pp.106.089003 [pii].

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Anke Reinders or John Ward.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Reinders, A., Ward, J. SUC1’s mode of low-affinity transport. Nat. Plants 9, 856–857 (2023). https://doi.org/10.1038/s41477-023-01431-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41477-023-01431-y

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing