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Exosomes deliver ROS for regeneration

Nature Cell Biology volume 20, pages 225–226 (2018)Cite this article

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Inflammation and reactive oxygen species (ROS) production after central nervous system injury are thought to enhance tissue damage and hamper neuronal regeneration. Evidence now suggests that NADPH2 oxidase delivery from macrophages to injured neurons through extracellular vesicles, promotes ROS signalling and axon recovery.

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Fig. 1: ROS signalling in sensory nerve regeneration.

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  1. Institute of Developmental Biology and Neurobiology (IDN), Biology of Extracellular Vesicles Group, Johannes Gutenberg University Mainz, Mainz, Germany

    Eva-Maria Krämer-Albers

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  1. Eva-Maria Krämer-Albers
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Correspondence to Eva-Maria Krämer-Albers.

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Krämer-Albers, EM. Exosomes deliver ROS for regeneration. Nat Cell Biol 20, 225–226 (2018). https://doi.org/10.1038/s41556-018-0048-9

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