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STEM CELLS

Long noncoding RNAs in gut stem cells

Nature Cell Biology volume 20, pages 1106–1107 (2018)Cite this article

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The intestinal crypt has become the prototype compartment to investigate adult stem cell biology, and the list of identified intestinal stem cell (ISC) markers is already extensive. A comprehensive study now uncovers an additional layer in ISC regulation by introducing long noncoding RNA lncGata6 to the stem cell repertoire.

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Fig. 1: Function of intestinal stem cell specific lncGata6.

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Authors and Affiliations

  1. Biomedical Sciences Research Center ‘Alexander Fleming’, Vari, Greece

    Pantelis Hatzis

  2. Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands

    Hugo J. G. Snippert

  3. Oncode Institute, Utrecht, the Netherlands

    Hugo J. G. Snippert

Authors
  1. Pantelis Hatzis
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  2. Hugo J. G. Snippert
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Correspondence to Pantelis Hatzis or Hugo J. G. Snippert.

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The authors declare no competing interests.

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Hatzis, P., Snippert, H.J.G. Long noncoding RNAs in gut stem cells. Nat Cell Biol 20, 1106–1107 (2018). https://doi.org/10.1038/s41556-018-0208-y

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