The synthesis of natural products with important biological properties has always fascinated chemists, but the development of rapid, efficient and stereoselective transformations remains challenging. Now, a strategy has been developed to produce several strychnan alkaloids through formation of a common bridged morphan core structure.
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Canesi, S. Total synthesis of strychnan alkaloids. Nat. Chem. 15, 1054–1055 (2023). https://doi.org/10.1038/s41557-023-01259-1
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DOI: https://doi.org/10.1038/s41557-023-01259-1