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Protein crystal design

Genetically encoded protein crystals by hierarchical design

Nature Materials volume 22, pages 1439–1440 (2023)Cite this article

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Three protein interaction surfaces are computationally designed into one protein subunit to enable their accurate assembly into three-dimensional crystals with user-specified lattice architectures.

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Fig. 1: Assembly and properties of de novo designed protein crystals.

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Authors and Affiliations

  1. Department of Bioproducts and Biosystems, Aalto University, Aalto, Finland

    Eduardo Anaya-Plaza & Mauri A. Kostiainen

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  1. Eduardo Anaya-Plaza
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  2. Mauri A. Kostiainen
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Correspondence to Mauri A. Kostiainen.

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The authors declare no competing interests.

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Anaya-Plaza, E., Kostiainen, M.A. Genetically encoded protein crystals by hierarchical design. Nat. Mater. 22, 1439–1440 (2023). https://doi.org/10.1038/s41563-023-01719-6

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