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Fungal pathogenesis

Fine-tuning fungal effector secretion

Nature Microbiology volume 8, pages 1613–1614 (2023)Cite this article

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The rice blast fungus Magnaporthe oryzae uses transfer RNA modifications to fine-tune effector protein secretion into host plant cells.

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Fig. 1: Unconventional secretion of M. oryzae cytoplasmic effectors is linked to thiolation of U34 in the anticodon of tRNAs.

References

  1. Redecker, D., Kodner, R. & Graham, L. E. Science 289, 1920–1921 (2000).

    Article  CAS  PubMed  Google Scholar 

  2. Stukenbrock, E. & Gurr, S. Nature 617, 31–34 (2023).

    Article  CAS  PubMed  Google Scholar 

  3. Zhang, S. & Xu, J.-R. PLoS Pathog. 10, e1003826 (2014).

    Article  PubMed  PubMed Central  Google Scholar 

  4. Li, G., Dulal, N., Gong, Z. & Wilson, R. A. Nat. Microbiol. https://doi.org/10.1038/s41564-023-01443-6 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Skamnioti, P. & Gurr, S. J. Trends Biotechnol. 27, 141–150 (2009).

    Article  CAS  PubMed  Google Scholar 

  6. Noller, H. F., Lancaster, L., Zhou, J. & Mohan, S. Nat. Struct. Mol. Biol. 24, 1021–1027 (2017).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Chujo, T. & Tomizawa, K. FEBS J. 288, 7096–7122 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Schaffrath, R. & Leidel, S. A. RNA Biol. 14, 1209–1222 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Smith, T. J., Giles, R. N. & Koutmou, K. S. Semin. Cell Dev. Biol. https://doi.org/10.1016/j.semcdb.2023.06.003 (2023).

    Article  PubMed  Google Scholar 

  10. Damon, J. R., Pincus, D. & Ploegh, H. L. Mol. Biol. Cell 26, 270–282 (2015).

    Article  PubMed  PubMed Central  Google Scholar 

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  1. John Innes Centre, Norwich Research Park, Norwich, UK

    Diane G. O. Saunders

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  1. Diane G. O. Saunders
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Correspondence to Diane G. O. Saunders.

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Saunders, D.G.O. Fine-tuning fungal effector secretion. Nat Microbiol 8, 1613–1614 (2023). https://doi.org/10.1038/s41564-023-01456-1

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