Neurons expressing corticotropin-releasing factor in the paraventricular nucleus of the hypothalamus of mice show increases and decreases in activity in response to aversive and appetitive stimuli.
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Kim, J. et al. Rapid, biphasic CRF neuronal responses encode positive and negative valence. Nat. Neurosci. https://doi.org/10.1038/s41593-019-0342-2 (2019)
Yuan, Y. et al. Reward inhibits paraventricular CRH neurons to relieve stress. Curr. Biol. https://doi.org/10.1016/j.cub.2019.02.048 (2019)
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Bray, N. Taking the good with the bad. Nat Rev Neurosci 20, 250–251 (2019). https://doi.org/10.1038/s41583-019-0159-8
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DOI: https://doi.org/10.1038/s41583-019-0159-8