Identifying the ways that a study sample is not representative is essential for maximizing the generalizability of findings to the population. A new method proposes discerning non-representativeness in large-scale genetic studies by comparing the genotypes of closely related participants.
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Adams, M.J. Leveraging family relatedness to detect participation bias in genetic studies. Nat Genet 55, 1254–1255 (2023). https://doi.org/10.1038/s41588-023-01440-9
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DOI: https://doi.org/10.1038/s41588-023-01440-9