The genetic background of pediatric acute myeloid leukemia (AML) does not fit with classification systems developed for adult AML. This study investigates the genetic background of pediatric AML and proposes a genomic framework for improved classification and risk stratification based on the driver alterations.
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References
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This is a summary of: Umeda, M. et al. A new genomic framework to categorize pediatric acute myeloid leukemia. Nat. Genet. https://doi.org/10.1038/s41588-023-01640-3 (2024).
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New genomic classification of pediatric acute myeloid leukemia. Nat Genet 56, 202–203 (2024). https://doi.org/10.1038/s41588-023-01639-w
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DOI: https://doi.org/10.1038/s41588-023-01639-w