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GENE REGULATION

MicroRNA says no to mass production

Cell-type-specific regulation of gene expression by transcription factors is a fundamental principle of biology. New findings show that microRNA-mediated control of target-gene expression is also dependent on the cellular context.

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Fig. 1: A multitude of mechanisms contribute to the cellular-context dependence of microRNA-mediated gene regulation.

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Correspondence to Changchun Xiao.

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Chen, P., Liao, K. & Xiao, C. MicroRNA says no to mass production. Nat Immunol 19, 1040–1042 (2018). https://doi.org/10.1038/s41590-018-0215-y

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