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Humoral immunity goes hormonal

Nature Immunology volume 19, pages 1044–1046 (2018)Cite this article

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Studies of mice demonstrate a link between the female hormone estrogen and protection against bacteremia and sepsis through the induction of natural antibodies to Eshcerichia coli.

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Fig. 1: Female mice produce nAbs that provide protection against pathogenic infection with E. coli in response to estrogen.

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Authors and Affiliations

  1. Department of Immunology, Genentech, South San Francisco, CA, USA

    Joseph Chavarria-Smith & Menno van Lookeren Campagne

  2. Department of Infectious Diseases, Genentech, South San Francisco, CA, USA

    Wouter L. W. Hazenbos

Authors
  1. Joseph Chavarria-Smith
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  2. Wouter L. W. Hazenbos
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  3. Menno van Lookeren Campagne
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Corresponding author

Correspondence to Menno van Lookeren Campagne.

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Competing interests

J.C.-S., W.L.W.H. and M.v.L.C. are employees of Genentech.

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Chavarria-Smith, J., Hazenbos, W.L.W. & van Lookeren Campagne, M. Humoral immunity goes hormonal. Nat Immunol 19, 1044–1046 (2018). https://doi.org/10.1038/s41590-018-0216-x

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