Cell Stem Cell 22, 941–950 (2018)
Transplantation of human spinal cord–derived neural stem cells is safe and may be of therapeutic benefit in individuals with chronic spinal cord injury (CSI).
For individuals with CSI, currently no therapy exists that results in improvement of motor or sensory function, although some cell therapies have shown promise. Joseph Ciacci and colleagues show for the first time in four individuals with CSI that injection with human spinal cord–derived neural stem cells is safe. Furthermore, three of the individuals that received the treatment saw some improvement in motor or sensory function.
The study provides promise for development of stem cell therapies for CSI.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Stower, H. Cell therapy for spinal cord injury. Nat Med 24, 1088 (2018). https://doi.org/10.1038/s41591-018-0155-y
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41591-018-0155-y
This article is cited by
-
Curcumin Improves Human Umbilical Cord-Derived Mesenchymal Stem Cell Survival via ERK1/2 Signaling and Promotes Motor Outcomes After Spinal Cord Injury
Cellular and Molecular Neurobiology (2022)
