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An exercise-induced messenger boosts memory in Alzheimer’s disease

Nature Medicine volume 25, pages 20–21 (2019)Cite this article

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An exercise-linked hormone, FNDC5/irisin, mediates the benefit of exercise in Alzheimer’s disease models by enhancing synaptic plasticity and memory.

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Fig. 1: Exercise-induced FNDC5/irisin prevents decline in cognitive function.

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Authors and Affiliations

  1. Gladstone Institutes, Department of Neurology, University of California San Francisco, San Francisco CA, USA

    Xu Chen & Li Gan

  2. Helen and Robert Appel Alzheimer’s Disease Research Institute, Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA

    Li Gan

Authors
  1. Xu Chen
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  2. Li Gan
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Correspondence to Li Gan.

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Competing interests

L.G is a cofounder of Aeton Therapeutics, Inc.

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Chen, X., Gan, L. An exercise-induced messenger boosts memory in Alzheimer’s disease. Nat Med 25, 20–21 (2019). https://doi.org/10.1038/s41591-018-0311-4

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