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Cancer therapy

Immunotherapy at all stages of hepatocellular carcinoma

A flurry of emerging treatment options is transforming the therapeutic landscape of hepatocellular carcinoma; two new studies highlight the complexities and gaps in knowledge, but also hint at a greater understanding of how to apply immunotherapy in early and advanced disease.

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Correspondence to David J. Pinato.

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Competing interests

D.J.P. received lecture fees from ViiV Healthcare, Bayer Healthcare, BMS, Roche, Eisai and Falk Foundation; travel expenses from BMS and Bayer Healthcare; consulting fees for Mina Therapeutics, EISAI, Roche, DaVolterra, Mursla, Exact Sciences and Astra Zeneca; and research funding (to their institution) from MSD and BMS. A.D. received educational support for congress attendance from Roche.

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Pinato, D.J., Fulgenzi, C.A.M. & D’Alessio, A. Immunotherapy at all stages of hepatocellular carcinoma. Nat Med 30, 640–641 (2024). https://doi.org/10.1038/s41591-024-02828-8

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