Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

Climate change and health: understanding mechanisms will inform mitigation and prevention strategies

Nature Medicine (2024)Cite this article

Subjects

The cellular and molecular mechanisms underlying the health impacts of climate change must be better understood in order to plan interventions that mitigate harm.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Cellular and molecular mechanisms of damage in climate-related health outcomes.

References

  1. Romanello, M. et al. Lancet 402, 2346–2394 (2023).

    Article  PubMed  Google Scholar 

  2. Cheng, B. J. et al. Environ. Int. 183, 108358 (2023).

    Article  PubMed  Google Scholar 

  3. Ghio, A. J. et al. Occup. Environ. Med. 69, 170–175 (2012).

    Article  PubMed  Google Scholar 

  4. Zhang, Q. et al. Proc. Biol. Sci. 290, 20231768 (2023).

    CAS  PubMed  Google Scholar 

  5. Jacobs, P. J., Oosthuizen, M. K., Mitchell, C., Blount, J. D. & Bennett, N. C. J. Therm. Biol. 98, 102958 (2021).

    Article  CAS  PubMed  Google Scholar 

  6. Choi, J. H. et al. J. Vet. Sci. 5, 11–18 (2004).

    Article  PubMed  Google Scholar 

  7. Fang, W. et al. Environ. Int. 181, 108247 (2023).

    Article  CAS  PubMed  Google Scholar 

  8. Kamps, J. L. & Varela, R. E. Diabetes Res. Clin. Pract. 88, 234–241 (2010).

    Article  PubMed  Google Scholar 

  9. Popov, L. D. J. Cell. Mol. Med. 24, 4892–4899 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Voituron, Y., Servais, S., Romestaing, C., Douki, T. & Barre, H. Cryobiology 52, 74–82 (2006).

    Article  CAS  PubMed  Google Scholar 

  11. Orogo, A. M. et al. J. Biol. Chem. 292, 11348 (2017).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Murray, K. O., Clanton, T. L. & Horowitz, M. Exp. Physiol. 107, 1144–1158 (2022).

    Article  CAS  PubMed  Google Scholar 

  13. Cardenas, A., Fadadu, R. & Bunyavanich, S. J. Allergy Clin. Immunol. 152, 1060–1072 (2023).

    Article  CAS  PubMed  Google Scholar 

  14. Xu, R. et al. Environ. Int. 171, 107704 (2023).

    Article  CAS  PubMed  Google Scholar 

  15. Xu, Z. et al. Int. J. Biometeorol. 58, 239–247 (2014).

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

D.P. was supported by the National Cancer Institute (grant U54CA267776). R.M.P. was supported by the National Institute of Environmental Health Sciences (NIEHS) (grant R00 ES033742). A.K. was supported by the NIEHS (R00 ES030749).

Author information

Authors and Affiliations

  1. Institute for Health Equity Research, Department of Population Health Science and Policy and the Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York City, NY, USA

    Diddier Prada

  2. Department of Environmental Health, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA, USA

    Andrea A. Baccarelli

  3. Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York City, NY, USA

    Allison Kupsco & Robbie M. Parks

Authors
  1. Diddier Prada
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Andrea A. Baccarelli
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Allison Kupsco
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Robbie M. Parks
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Robbie M. Parks.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Prada, D., Baccarelli, A.A., Kupsco, A. et al. Climate change and health: understanding mechanisms will inform mitigation and prevention strategies. Nat Med (2024). https://doi.org/10.1038/s41591-024-02925-8

Download citation

  • Published:

  • DOI: https://doi.org/10.1038/s41591-024-02925-8

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research