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Chromatin

Chd1 bends over backward to remodel

Chd1 is a highly conserved chromatin remodeler found across all eukaryotic species. A recent study shows the structural changes that take place when yeast Chd1 binds to its nucleosomal substrate and reveals how they relate to remodeler function.

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Fig. 1: Structural insight into Chd1 nucleosome binding.

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Correspondence to Michaela M. Smolle.

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Smolle, M.M. Chd1 bends over backward to remodel. Nat Struct Mol Biol 25, 2–3 (2018). https://doi.org/10.1038/s41594-017-0014-4

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