Nanobodies have emerged as highly versatile and useful binding molecules in biomedical research. A technical report describes a cost- and time-effective in vitro platform that facilitates the generation of desired nanobodies, including conformationally selective nanobodies against agonist-bound G-protein-coupled receptors (GPCRs).
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Rothbauer, U. Speed up to find the right ones: rapid discovery of functional nanobodies. Nat Struct Mol Biol 25, 199–201 (2018). https://doi.org/10.1038/s41594-018-0038-4
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DOI: https://doi.org/10.1038/s41594-018-0038-4
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