A method to identify and analyze clonal hematopoiesis in clinical blood samples at single-cell resolution reveals cell-intrinsic and paracrine effects of DNMT3A mutations in circulating monocytes, T cells and natural killer cells in the setting of heart failure.
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Chavkin, N.W., Evans, M.A. & Walsh, K. How clonal hematopoiesis promotes inflammation at a single-cell level. Nat Cardiovasc Res 2, 801–802 (2023). https://doi.org/10.1038/s44161-023-00323-w
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DOI: https://doi.org/10.1038/s44161-023-00323-w