Focus
Checks and Balances in the Immune System
- Focus issue:
- October 2012 Volume 13, No 10
Immune cells drive a potent response after encounter with a pathogen. Nature Immunology presents a series of specially commissioned articles that discuss the metabolic requirements of immune responses and the regulatory circuits that balance eradication of the pathogen with minimal collateral damage to the host.
Editorial
Focus on Checks and Balances in the Immune System
A balancing act - p901
doi:10.1038/ni.2430
Full Text - An inflammatory assemblage | PDF (161 KB) - An inflammatory assemblage
Commentary
Focus on Checks and Balances in the Immune System
Maintaining system homeostasis: the third law of Newtonian immunology - pp902 - 906
Ronald N. Germain
doi:10.1038/ni.2404
Full Text - Maintaining system homeostasis: the third law of Newtonian immunology | PDF (3,090 KB) - Maintaining system homeostasis: the third law of Newtonian immunology
Reviews
Focus on Checks and Balances in the Immune System
Metabolic checkpoints in activated T cells - pp907 - 915
Ruoning Wang & Douglas R Green
doi:10.1038/ni.2386
Abstract - Metabolic checkpoints in activated T cells | Full Text - Metabolic checkpoints in activated T cells | PDF (724 KB) - Metabolic checkpoints in activated T cells
Focus on Checks and Balances in the Immune System
Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways - pp916 - 924
Peter J Murray & Stephen T Smale
doi:10.1038/ni.2391
Abstract - Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways | Full Text - Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways | PDF (836 KB) - Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways
Focus on Checks and Balances in the Immune System
From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines - pp925 - 931
Jacques Banchereau, Virginia Pascual & Anne O'Garra
doi:10.1038/ni.2406
Abstract - From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines | Full Text - From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines | PDF (1,321 KB) - From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines
Focus on Checks and Balances in the Immune System
The price of immunity - pp932 - 938
Romina S Goldszmid & Giorgio Trinchieri
doi:10.1038/ni.2422
Abstract - The price of immunity | Full Text - The price of immunity | PDF (574 KB) - The price of immunity