Volume 34 Issue 1, January 2024

The image shows the tragic story of the Greek soldier Philippides, who brought the victory message of the battle of Marathon to Athens but died after 26 miles and 385 yards (42.195 km) exhaustive running. In fact, human muscle developed mitochondrial protein lactylation as a preventive mechanism for such disaster. See page 13–30 by Yunzi Mao et al. for details.

Research Highlight

Rpd3S meets the nucleosome

Michael J. Carrozza
Jerry L. Workman
Research Highlight 20 Nov 2023
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Caught in the middle: MARCH5 mediates PD-1-induced IL-2R degradation

Xinghao Wang
Weiping Zou
Research Highlight 04 Dec 2023
Swiss army knife T cell: one T cell many tumor targets

Abdulla Berjis
Deeksha Muthumani
Carl H. June
Research Highlight 04 Sept 2023
Chromosomal instability drives immunosuppression and metastatic dissemination

Ilio Vitale
Claudia Galassi
Lorenzo Galluzzi
Research Highlight 22 Sept 2023
Learning human liver biology in humanized mice

Brandon M. Lehrich
Satdarshan P. Monga
Research Highlight 20 Sept 2023
LICOB: a powerful organoid platform for drug discovery

Haojie Jin
Zhen Sun
René Bernards
Research Highlight 20 Sept 2023

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Article

Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation

Yunzi Mao
Jiaojiao Zhang
Shimin Zhao
Article Open Access 02 Jan 2024
Engineered poly(A)-surrogates for translational regulation and therapeutic biocomputation in mammalian cells

Jiawei Shao
Shichao Li
Mingqi Xie
Article Open Access 04 Jan 2024
Transport and inhibition mechanism for VMAT2-mediated synaptic vesicle loading of monoamines

Yuwei Wang
Pei Zhang
Qianhui Qu
Article Open Access 02 Jan 2024
ZNF689 deficiency promotes intratumor heterogeneity and immunotherapy resistance in triple-negative breast cancer

Li-Ping Ge
Xi Jin
Yi-Zhou Jiang
Article 02 Jan 2024

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Letter to the Editor

Structural basis for activation and filamentation of glutaminase

Chen-Jun Guo
Zi-Xuan Wang
Ji-Long Liu
Letter to the Editor Open Access 13 Oct 2023
Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity

Le Zheng
Tingting Yang
Xiaoyun Ji
Letter to the Editor Open Access 06 Nov 2023
Human SIDT1 mediates dsRNA uptake via its phospholipase activity

Cai-Rong Sun
Da Xu
Cong-Zhao Zhou
Letter to the Editor 06 Nov 2023

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Correction

Author Correction: BacFlash signals acid-resistance gene expression in bacteria

Di Wu
Wenfeng Qi
Xianhua Wang
Correction 11 Dec 2023
Publisher Correction: Sanofi-Cell Research outstanding paper award of 2022

Correction 07 Dec 2023

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Volume 34 Issue 1, January 2024

Research Highlight

Rpd3S meets the nucleosome

Caught in the middle: MARCH5 mediates PD-1-induced IL-2R degradation

Swiss army knife T cell: one T cell many tumor targets

Chromosomal instability drives immunosuppression and metastatic dissemination

Learning human liver biology in humanized mice

LICOB: a powerful organoid platform for drug discovery

Article

Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation

Engineered poly(A)-surrogates for translational regulation and therapeutic biocomputation in mammalian cells

Transport and inhibition mechanism for VMAT2-mediated synaptic vesicle loading of monoamines

ZNF689 deficiency promotes intratumor heterogeneity and immunotherapy resistance in triple-negative breast cancer

Letter to the Editor

Structural basis for activation and filamentation of glutaminase

Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity

Human SIDT1 mediates dsRNA uptake via its phospholipase activity

Correction

Author Correction: BacFlash signals acid-resistance gene expression in bacteria

Publisher Correction: Sanofi-Cell Research outstanding paper award of 2022

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