Genes & Immunity Genes & Immunity emphasizes studies that demonstrate genetic, genomic or functional variation in the immune system, and assist our understanding of how the basic control over the immune system varies between individuals both in health and disease. The emerging role for genes outside the MHC will be of particular interest. http://feeds.nature.com/gene/rss/current Nature Publishing Group en © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Genes & Immunity © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com Genes & Immunity https://www.nature.com/uploads/product/gene/rss.gif http://feeds.nature.com/gene/rss/current <![CDATA[Chemoimmunotherapy combinations: translating basic knowledge into clinical successes]]> https://www.nature.com/articles/s41435-024-00264-9 Genes & Immunity, Published online: 13 March 2024; doi:10.1038/s41435-024-00264-9

While chemotherapeutic agents were long solely associated with immunosuppression, clinical data demonstrate that the combination of some chemotherapies with immunomodulators can be beneficial against cancer. Defining combinations featuring optimal anticancer activity along with minimal toxicity remains however a major challenge. Clinical evidence suggests that immune responses in patients treated with combination therapies are associated with progression-free survival. Progress in understanding the mechanisms responsible for anticancer immune responses following chemotherapy administration facilitated the translation of relevant chemoimmunotherapy combinations in the clinic.]]>
Lionel Apetoh doi:10.1038/s41435-024-00264-9 Genes & Immunity, Published online: 2024-03-13; | doi:10.1038/s41435-024-00264-9 2024-03-13 Genes & Immunity 10.1038/s41435-024-00264-9 https://www.nature.com/articles/s41435-024-00264-9
<![CDATA[RNA processing modification mediated subtypes illustrate the distinctive features of tumor microenvironment in hepatocellular carcinoma]]> https://www.nature.com/articles/s41435-024-00265-8 Genes & Immunity, Published online: 12 March 2024; doi:10.1038/s41435-024-00265-8

RNA processing modification mediated subtypes illustrate the distinctive features of tumor microenvironment in hepatocellular carcinoma]]>
Xinhui LiShan LiuLaibin ZouMin DaiChaobei Zhu doi:10.1038/s41435-024-00265-8 Genes & Immunity, Published online: 2024-03-12; | doi:10.1038/s41435-024-00265-8 2024-03-12 Genes & Immunity 10.1038/s41435-024-00265-8 https://www.nature.com/articles/s41435-024-00265-8
<![CDATA[Pivotal role of BCL11B in the immune, hematopoietic and nervous systems: a review of the BCL11B-associated phenotypes from the genetic perspective]]> https://www.nature.com/articles/s41435-024-00263-w Genes & Immunity, Published online: 12 March 2024; doi:10.1038/s41435-024-00263-w

Pivotal role of BCL11B in the immune, hematopoietic and nervous systems: a review of the BCL11B-associated phenotypes from the genetic perspective]]>
José María García-AznarSara Alonso AlvarezTeresa Bernal del Castillo doi:10.1038/s41435-024-00263-w Genes & Immunity, Published online: 2024-03-12; | doi:10.1038/s41435-024-00263-w 2024-03-12 Genes & Immunity 10.1038/s41435-024-00263-w https://www.nature.com/articles/s41435-024-00263-w
<![CDATA[Intratumoral NK cell delivery combined with neutralization of the NKG2A pathway as treatment for solid cancer]]> https://www.nature.com/articles/s41435-024-00267-6 Genes & Immunity, Published online: 09 March 2024; doi:10.1038/s41435-024-00267-6

Intratumoral NK cell delivery combined with neutralization of the NKG2A pathway as treatment for solid cancer]]>
Ignacio MeleroCarmen MolinaCristina EguizabalMaite Alvarez doi:10.1038/s41435-024-00267-6 Genes & Immunity, Published online: 2024-03-09; | doi:10.1038/s41435-024-00267-6 2024-03-09 Genes & Immunity 10.1038/s41435-024-00267-6 https://www.nature.com/articles/s41435-024-00267-6
<![CDATA[Getting under the skin: resident memory CD8<sup>+</sup> T cells have a second residence in the draining lymph node]]> https://www.nature.com/articles/s41435-024-00266-7 Genes & Immunity, Published online: 08 March 2024; doi:10.1038/s41435-024-00266-7

Getting under the skin: resident memory CD8+ T cells have a second residence in the draining lymph node]]>
+ T cells have a second residence in the draining lymph node]]> Teresa NeuwirthAzuah L. GonzalezEmilie Fisher-GuptaGeorg Stary doi:10.1038/s41435-024-00266-7 Genes & Immunity, Published online: 2024-03-08; | doi:10.1038/s41435-024-00266-7 2024-03-08 Genes & Immunity 10.1038/s41435-024-00266-7 https://www.nature.com/articles/s41435-024-00266-7
<![CDATA[Cytokine profiling and transcriptomics in mononuclear cells define immune variants in Meniere Disease]]> https://www.nature.com/articles/s41435-024-00260-z Genes & Immunity, Published online: 23 February 2024; doi:10.1038/s41435-024-00260-z

Cytokine profiling and transcriptomics in mononuclear cells define immune variants in Meniere Disease]]>
Marisa FlookElena RojanoAlvaro Gallego-MartinezAlba Escalera-BalseraPatricia Perez-CarpenaM. del Carmen MoleonRocio Gonzalez-AguadoVictoria Rivero de JesusEmilio Domínguez-DuránLidia FrejoJuan A. G. RaneaJose Antonio Lopez-Escamez doi:10.1038/s41435-024-00260-z Genes & Immunity, Published online: 2024-02-23; | doi:10.1038/s41435-024-00260-z 2024-02-23 Genes & Immunity 10.1038/s41435-024-00260-z https://www.nature.com/articles/s41435-024-00260-z
<![CDATA[Epigenetic reprogramming of CAR T cells for in vivo functional persistence against solid tumors]]> https://www.nature.com/articles/s41435-024-00262-x Genes & Immunity, Published online: 22 February 2024; doi:10.1038/s41435-024-00262-x

Epigenetic reprogramming of CAR T cells for in vivo functional persistence against solid tumors]]>
Michael Saitakis doi:10.1038/s41435-024-00262-x Genes & Immunity, Published online: 2024-02-22; | doi:10.1038/s41435-024-00262-x 2024-02-22 Genes & Immunity 10.1038/s41435-024-00262-x https://www.nature.com/articles/s41435-024-00262-x
<![CDATA[Correction: Preclinical models of breast cancer: B6BC, a transplantable hormone receptor-positive C57BL/6 mouse cell line]]> https://www.nature.com/articles/s41435-024-00259-6 Genes & Immunity, Published online: 20 February 2024; doi:10.1038/s41435-024-00259-6

Correction: Preclinical models of breast cancer: B6BC, a transplantable hormone receptor-positive C57BL/6 mouse cell line]]>
Maria Perez-LanzonMaria Chiara MaiuriCarlos Lopez-OtinGuido Kroemer doi:10.1038/s41435-024-00259-6 Genes & Immunity, Published online: 2024-02-20; | doi:10.1038/s41435-024-00259-6 2024-02-20 Genes & Immunity 10.1038/s41435-024-00259-6 https://www.nature.com/articles/s41435-024-00259-6