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In a real-world Korean population without cardiovascular disease, the use of diuretics as firstline antihypertensive medication was not superior to other antihypertensive medications in terms of reducing long-term cardiovascular risk.
This review provides a broad survey of the applications, progress, and challenges of omics technologies (genomics, transcriptomics, proteomics, metabolomics, and microbiomics) in the field of hypertension and resistant hypertension.
Hypoxia inducible factor(HIF) activation enhances sodium excretion following high salt diet in mice through upregulation of cyclooxygenase 2(COX2) in the renal medulla and therefore maintains body sodium homeostasis.
Treatment with sacubitril/valsartan is effective and provided superior blood pressure (BP) reductions with a higher proportion of patients achieving target BP goals versus olmesartan in Japanese patients with mild-to-moderate essential hypertension.
Skeletal muscle mass index was negatively associated with circulating calciprotein particle levels. Reduced skeletal muscle mass may be an independent endogenous factor that elevates circulating calciprotein particle levels.
