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  • Article |

    • Alexis J. Combes
    • , Tristan Courau
    • , Nicholas F. Kuhn
    • , Kenneth H. Hu
    • , Arja Ray
    • , William S. Chen
    • , Nayvin W. Chew
    • , Simon J. Cleary
    • , Divyashree Kushnoor
    • , Gabriella C. Reeder
    • , Alan Shen
    • , Jessica Tsui
    • , Kamir J. Hiam-Galvez
    • , Priscila Muñoz-Sandoval
    • , Wandi S. Zhu
    • , David S. Lee
    • , Yang Sun
    • , Ran You
    • , Mélia Magnen
    • , Lauren Rodriguez
    • , K. W. Im
    • , Nina K. Serwas
    • , Aleksandra Leligdowicz
    • , Colin R. Zamecnik
    • , Rita P. Loudermilk
    • , Michael R. Wilson
    • , Chun J. Ye
    • , Gabriela K. Fragiadakis
    • , Mark R. Looney
    • , Vincent Chan
    • , Alyssa Ward
    • , Sidney Carrillo
    • , Michael Matthay
    • , David J. Erle
    • , Prescott G. Woodruff
    • , Charles Langelier
    • , Kirsten Kangelaris
    • , Carolyn M. Hendrickson
    • , Carolyn Calfee
    • , Arjun Arkal Rao
    •  & Matthew F. Krummel

  • Article |

    • Bryan A. Johnson
    • , Xuping Xie
    • , Adam L. Bailey
    • , Birte Kalveram
    • , Kumari G. Lokugamage
    • , Antonio Muruato
    • , Jing Zou
    • , Xianwen Zhang
    • , Terry Juelich
    • , Jennifer K. Smith
    • , Lihong Zhang
    • , Nathen Bopp
    • , Craig Schindewolf
    • , Michelle Vu
    • , Abigail Vanderheiden
    • , Emma S. Winkler
    • , Daniele Swetnam
    • , Jessica A. Plante
    • , Patricia Aguilar
    • , Kenneth S. Plante
    • , Vsevolod Popov
    • , Benhur Lee
    • , Scott C. Weaver
    • , Mehul S. Suthar
    • , Andrew L. Routh
    • , Ping Ren
    • , Zhiqiang Ku
    • , Zhiqiang An
    • , Kari Debbink
    • , Michael S. Diamond
    • , Pei Yong Shi
    • , Alexander N. Freiberg
    •  & Vineet D. Menachery

  • Where I Work |

    Leah Tsang helps to bring bird poisoners to justice as part of her role at Australia’s oldest museum.

    • James Mitchell Crow

  • Nature Briefing |

    Most citations of discredited Surgisphere research fail to mention retractions. Plus, why the world’s pandemic warning system failed when COVID hit and how uncertainty can sharpen our thinking.

    • Flora Graham

  • News & Views |

    A large-scale, high-resolution cell atlas of gene expression and regulation in human embryos enables innovative investigation of development through multi‑organ and multi‑modal analysis.

    • Felicia Kuperwaser
    •  & Itai Yanai

  • Obituary |

    Theoretician who simplified nuclear physics and revamped Japan’s science.

    • David Swinbanks

  • Career Column |

    Biomedical scientist Vladimira Foteva didn’t imagine she would be working with physicists at an Australian particle accelerator when she began her PhD, but the experience taught her the value of collaboration across disciplines.

    • Vladimira Foteva

  • Nature Briefing |

    Catnip activates cats’ opioid systems (and protects them from mosquitos). Plus, ten computer codes that transformed science and what new SARS-CoV-2 variants mean for schools.

    • Flora Graham

  • Article |

    • Nobuhiko Kayagaki
    • , Opher S. Kornfeld
    • , Bettina L. Lee
    • , Irma B. Stowe
    • , Karen O’Rourke
    • , Qingling Li
    • , Wendy Sandoval
    • , Donghong Yan
    • , Jing Kang
    • , Min Xu
    • , Juan Zhang
    • , Wyne P. Lee
    • , Brent S. McKenzie
    • , Gözde Ulas
    • , Jian Payandeh
    • , Merone Roose-Girma
    • , Zora Modrusan
    • , Rohit Reja
    • , Meredith Sagolla
    • , Joshua D. Webster
    • , Vicky Cho
    • , T. Daniel Andrews
    • , Lucy X. Morris
    • , Lisa A. Miosge
    • , Christopher C. Goodnow
    • , Edward M. Bertram
    •  & Vishva M. Dixit

  • Nature Podcast |

    Analysis of hundreds of thousands of job searches shows that recruiters will discriminate based on ethnicity and gender, and the neural circuitry behind a brief period of forgetting.

    • Benjamin Thompson
    •  & Nick Howe

  • Perspective |

    Unique biological traits of bats and adaptive evolution associated with flight confer immunotolerance of viral infection that may help to make bats special reservoir hosts for viruses.

    • Aaron T. Irving
    • , Matae Ahn
    • , Geraldine Goh
    • , Danielle E. Anderson
    •  & Lin-Fa Wang

  • Article |

    A reprogrammable mechanical metamaterial constructed of bistable unit cells that can be switched independently and reversibly between two stable states with distinct mechanical properties using magnetic actuation is demonstrated.

    • Tian Chen
    • , Mark Pauly
    •  & Pedro M. Reis

  • Article |

    Modelling and remote sensing show that by the end of the twenty-first century, lake heatwaves will be several degrees Celsius warmer and some will be months longer, with potentially major adverse consequences for lake ecosystems.

    • R. Iestyn Woolway
    • , Eleanor Jennings
    • , Tom Shatwell
    • , Malgorzata Golub
    • , Don C. Pierson
    •  & Stephen C. Maberly

  • Article |

    A stable, low-temperature water–gas shift catalyst is achieved by crowding platinum atoms and clusters on α-molybdenum carbide; the crowding protects the support from oxidation that would cause catalyst deactivation.

    • Xiao Zhang
    • , Mengtao Zhang
    • , Yuchen Deng
    • , Mingquan Xu
    • , Luca Artiglia
    • , Wen Wen
    • , Rui Gao
    • , Bingbing Chen
    • , Siyu Yao
    • , Xiaochen Zhang
    • , Mi Peng
    • , Jie Yan
    • , Aowen Li
    • , Zheng Jiang
    • , Xingyu Gao
    • , Sufeng Cao
    • , Ce Yang
    • , A. Jeremy Kropf
    • , Jinan Shi
    • , Jinglin Xie
    • , Mingshu Bi
    • , Jeroen A. van Bokhoven
    • , Yong-Wang Li
    • , Xiaodong Wen
    • , Maria Flytzani-Stephanopoulos
    • , Chuan Shi
    • , Wu Zhou
    •  & Ding Ma

  • Article |

    A dopamine neuron that underpins transient forgetting in Drosophila is activated by the presentation of interfering stimuli immediately before memory retrieval, modulating this retrieval by stimulating a dopamine receptor in mushroom body neurons.

    • John Martin Sabandal
    • , Jacob A. Berry
    •  & Ronald L. Davis

  • Article |

    Simultaneous mapping of activity across the cortex and dorsal striatum in mice shows that activity in each part of the striatum precisely mirrors that in topographically associated cortical regions, consistently across behavioural contexts.

    • Andrew J. Peters
    • , Julie M. J. Fabre
    • , Nicholas A. Steinmetz
    • , Kenneth D. Harris
    •  & Matteo Carandini

  • Article |

    It is experimentally shown that crystallographic defects may trap fractional charges, as well as topological states, in the bulk of topological crystalline insulators.

    • Christopher W. Peterson
    • , Tianhe Li
    • , Wentao Jiang
    • , Taylor L. Hughes
    •  & Gaurav Bahl

  • Article |

    An analysis of the search behaviour of recruiters on a Swiss online recruitment platform shows that jobseekers from minority ethnic groups are less likely to be contacted by recruiters, and also provides evidence of gender-based discrimination.

    • Dominik Hangartner
    • , Daniel Kopp
    •  & Michael Siegenthaler

  • Article |

    A large, open dataset containing parallel recordings from six visual cortical and two thalamic areas of the mouse brain is presented, from which the relative timing of activity in response to visual stimuli and behaviour is used to construct a hierarchy scheme that corresponds to anatomical connectivity data.

    • Joshua H. Siegle
    • , Xiaoxuan Jia
    • , Séverine Durand
    • , Sam Gale
    • , Corbett Bennett
    • , Nile Graddis
    • , Greggory Heller
    • , Tamina K. Ramirez
    • , Hannah Choi
    • , Jennifer A. Luviano
    • , Peter A. Groblewski
    • , Ruweida Ahmed
    • , Anton Arkhipov
    • , Amy Bernard
    • , Yazan N. Billeh
    • , Dillan Brown
    • , Michael A. Buice
    • , Nicolas Cain
    • , Shiella Caldejon
    • , Linzy Casal
    • , Andrew Cho
    • , Maggie Chvilicek
    • , Timothy C. Cox
    • , Kael Dai
    • , Daniel J. Denman
    • , Saskia E. J. de Vries
    • , Roald Dietzman
    • , Luke Esposito
    • , Colin Farrell
    • , David Feng
    • , John Galbraith
    • , Marina Garrett
    • , Emily C. Gelfand
    • , Nicole Hancock
    • , Julie A. Harris
    • , Robert Howard
    • , Brian Hu
    • , Ross Hytnen
    • , Ramakrishnan Iyer
    • , Erika Jessett
    • , Katelyn Johnson
    • , India Kato
    • , Justin Kiggins
    • , Sophie Lambert
    • , Jerome Lecoq
    • , Peter Ledochowitsch
    • , Jung Hoon Lee
    • , Arielle Leon
    • , Yang Li
    • , Elizabeth Liang
    • , Fuhui Long
    • , Kyla Mace
    • , Jose Melchior
    • , Daniel Millman
    • , Tyler Mollenkopf
    • , Chelsea Nayan
    • , Lydia Ng
    • , Kiet Ngo
    • , Thuyahn Nguyen
    • , Philip R. Nicovich
    • , Kat North
    • , Gabriel Koch Ocker
    • , Doug Ollerenshaw
    • , Michael Oliver
    • , Marius Pachitariu
    • , Jed Perkins
    • , Melissa Reding
    • , David Reid
    • , Miranda Robertson
    • , Kara Ronellenfitch
    • , Sam Seid
    • , Cliff Slaughterbeck
    • , Michelle Stoecklin
    • , David Sullivan
    • , Ben Sutton
    • , Jackie Swapp
    • , Carol Thompson
    • , Kristen Turner
    • , Wayne Wakeman
    • , Jennifer D. Whitesell
    • , Derric Williams
    • , Ali Williford
    • , Rob Young
    • , Hongkui Zeng
    • , Sarah Naylor
    • , John W. Phillips
    • , R. Clay Reid
    • , Stefan Mihalas
    • , Shawn R. Olsen
    •  & Christof Koch

  • Article |

    Observations from the International Space Station show a blue jet that is initiated by an intense blue flash in the top of a thunderstorm cloud.

    • Torsten Neubert
    • , Olivier Chanrion
    • , Matthias Heumesser
    • , Krystallia Dimitriadou
    • , Lasse Husbjerg
    • , Ib Lundgaard Rasmussen
    • , Nikolai Østgaard
    •  & Victor Reglero

  • Article |

    In aged mice, inhibition of prostaglandin E2 (PGE2) signalling through its receptor EP2 improves cellular bioenergetics, reduces inflammatory responses and restores hippocampal plasticity to youthful levels, resulting in an improvement in spatial memory and cognition.

    • Paras S. Minhas
    • , Amira Latif-Hernandez
    • , Melanie R. McReynolds
    • , Aarooran S. Durairaj
    • , Qian Wang
    • , Amanda Rubin
    • , Amit U. Joshi
    • , Joy Q. He
    • , Esha Gauba
    • , Ling Liu
    • , Congcong Wang
    • , Miles Linde
    • , Yuki Sugiura
    • , Peter K. Moon
    • , Ravi Majeti
    • , Makoto Suematsu
    • , Daria Mochly-Rosen
    • , Irving L. Weissman
    • , Frank M. Longo
    • , Joshua D. Rabinowitz
    •  & Katrin I. Andreasson

  • Article |

    In macaque motor cortex, moment-to-moment fluctuations in neurally derived decision variables are tightly linked to decision state and predict behavioural choices with better accuracy than condition-averaged decision variables or the visual stimulus alone, and can be used to distinguish between different models of decision making.

    • Diogo Peixoto
    • , Jessica R. Verhein
    • , Roozbeh Kiani
    • , Jonathan C. Kao
    • , Paul Nuyujukian
    • , Chandramouli Chandrasekaran
    • , Julian Brown
    • , Sania Fong
    • , Stephen I. Ryu
    • , Krishna V. Shenoy
    •  & William T. Newsome

  • Article |

    It is experimentally shown that topological states exist at crystallographic defects in the bulk and that disclination defects trap fractional charges characteristic of topological crystalline insulators.

    • Yang Liu
    • , Shuwai Leung
    • , Fei-Fei Li
    • , Zhi-Kang Lin
    • , Xiufeng Tao
    • , Yin Poo
    •  & Jian-Hua Jiang

  • Article |

    A method of tracking break-induced replication reveals the details of this repair process and shows that it can be impaired by certain genomic elements and by transcription.

    • Liping Liu
    • , Zhenxin Yan
    • , Beth A. Osia
    • , Jerzy Twarowski
    • , Luyang Sun
    • , Juraj Kramara
    • , Rosemary S. Lee
    • , Sandeep Kumar
    • , Rajula Elango
    • , Hanzeng Li
    • , Weiwei Dang
    • , Grzegorz Ira
    •  & Anna Malkova

  • News Feature |

    From Fortran to arXiv.org, these advances in programming and platforms sent biology, climate science and physics into warp speed.

    • Jeffrey M. Perkel

  • News & Views |

    Immune cells called macrophages have been found to shut down major metabolic pathways during ageing. Restoring metabolism in these cells is sufficient to alleviate age-associated cognitive decline in mice.

    • Jonas J. Neher

  • News & Views |

    A device has been developed that consists of mechanical bits, analogous to the magnetic bits used in computer hard drives. Information encoded in the bits programs the mechanical properties of the device.

    • Corentin Coulais

  • News & Views |

    Fractional electric charges have been observed at crystal defects in artificial structures resembling materials called topological crystalline insulators. Such fractional charges could have various engineering applications.

    • Carmine Ortix

  • Career News |

    Referees for the US National Institutes of Health report engaging less during virtual panel meetings — but most think review quality doesn’t suffer.

    • Dalmeet Singh Chawla