Volume 42
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No. 4 April 2024
Whole-body imagingImage of a whole mouse body with depth color-coding of a neuronal marker. Mai et al. present wildDISCO, a method for whole-body imaging compatible with standard IgG antibody labeling.
See Mai et al.
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No. 3 March 2024
Point-of-care monitoringA miniaturized ultrasonic system can provide full-body monitoring and diagnosis. Lin et al. engineer a soft, wireless ultrasound device to measure deep body signals in moving subjects, offering a hands-free solution for continuous, comprehensive health tracking at the point of care.
See Lin et al.
Collection
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No. 2 February 2024
Focus on protein engineeringArtistic impression of the three data types key to machine learning for functional protein design: structure, sequence and labels. The structure of carbonic anhydrase is shown in front of a background composed of amino acid letters representing sequence data. The hue overlay represents a fitness landscape that experimentally acquired labels help to map.
See Notin et al.
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No. 1 January 2024
Multi-immersion mirror objectivesNeurons in the mouse hippocampus imaged with the Schmidt objective. Voigt et al. develop a multi-immersion objective based on a mirror instead of a lens.
See Voigt et al.