Nature Chemistry Nature Chemistry is a monthly journal dedicated to publishing high-quality papers that describe the most significant and cutting-edge research in all areas of chemistry. As well as reflecting the traditional core subjects of analytical, inorganic, organic and physical chemistry, the journal features a broad range of chemical research including, but not limited to, bioinorganic and bioorganic chemistry, catalysis, computational and theoretical chemistry, environmental chemistry, green chemistry, medicinal chemistry, organometallic chemistry, polymer chemistry, supramolecular chemistry and surface chemistry. Other multidisciplinary topics such as nanotechnology, chemical biology and materials chemistry are also featured. http://feeds.nature.com/nchem/rss/current Nature Publishing Group en © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature Chemistry © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com Nature Chemistry https://www.nature.com/uploads/product/nchem/rss.png http://feeds.nature.com/nchem/rss/current <![CDATA[Cage escape governs photoredox reaction rates and quantum yields]]> https://www.nature.com/articles/s41557-024-01482-4 Nature Chemistry, Published online: 18 March 2024; doi:10.1038/s41557-024-01482-4

The spontaneous recombination of photogenerated radicals surrounded by solvent molecules is an important energy-wasting elementary step in photoredox reactions. Now the decisive role that cage escape plays in these reactions is shown in three benchmark photocatalytic reactions, with quantitative correlations observed between photoredox product formation rates and cage escape quantum yields.]]>
Cui WangHan LiTobias H. BürginOliver S. Wenger doi:10.1038/s41557-024-01482-4 Nature Chemistry, Published online: 2024-03-18; | doi:10.1038/s41557-024-01482-4 2024-03-18 Nature Chemistry 10.1038/s41557-024-01482-4 https://www.nature.com/articles/s41557-024-01482-4
<![CDATA[High-throughput and proteome-wide discovery of endogenous biomolecular condensates]]> https://www.nature.com/articles/s41557-024-01485-1 Nature Chemistry, Published online: 18 March 2024; doi:10.1038/s41557-024-01485-1

High-throughput proteome-wide methods for identifying endogenous proteins that phase separate or partition into condensates during certain physiological events are needed but remain a challenge. Now, a high-throughput, unbiased and quantitative strategy can identify endogenous biomolecular condensates and screen proteins involved in phase separation on a proteome-wide scale.]]>
Pengjie LiPeng ChenFukang QiJinyun ShiWenjie ZhuJiashuo LiPeng ZhangHan XieLina LiMengcheng LeiXueqing RenWenhui WangLiang ZhangXufu XiangYiwei ZhangZhaolong GaoXiaojun FengWei DuXin LiuLimin XiaBi-Feng LiuYiwei Li doi:10.1038/s41557-024-01485-1 Nature Chemistry, Published online: 2024-03-18; | doi:10.1038/s41557-024-01485-1 2024-03-18 Nature Chemistry 10.1038/s41557-024-01485-1 https://www.nature.com/articles/s41557-024-01485-1
<![CDATA[RNA modulates hnRNPA1A amyloid formation mediated by biomolecular condensates]]> https://www.nature.com/articles/s41557-024-01467-3 Nature Chemistry, Published online: 12 March 2024; doi:10.1038/s41557-024-01467-3

The underlying mechanism for how heterotypic protein–RNA interactions modulate the liquid to amyloid transition of hnRNPA1A, a protein involved in amyotrophic lateral sclerosis, has so far remained elusive. Now characterization of hnRNPA1A condensate formation and aggregation in vitro reveals that the RNA/protein stoichiometry affects the molecular pathways leading to amyloid formation.]]>
Chiara MorelliLenka FaltovaUmberto Capasso PalmieroKatarzyna MakasewiczMarcell PappRaphaël P. B. JacquatDorothea PinotsiPaolo Arosio doi:10.1038/s41557-024-01467-3 Nature Chemistry, Published online: 2024-03-12; | doi:10.1038/s41557-024-01467-3 2024-03-12 Nature Chemistry 10.1038/s41557-024-01467-3 https://www.nature.com/articles/s41557-024-01467-3
<![CDATA[Porphyrin-fused graphene nanoribbons]]> https://www.nature.com/articles/s41557-024-01477-1 Nature Chemistry, Published online: 08 March 2024; doi:10.1038/s41557-024-01477-1

The insertion of metal atoms and heteroaromatic units provides a way to tune the optical, electronic and magnetic properties of graphene nanoribbons. Now the synthesis of a porphyrin-fused graphene nanoribbon with a narrow bandgap and high charge mobility has been achieved, and this material used to fabricate field-effect and single-electron transistors.]]>
Qiang ChenAlessandro LodiHeng ZhangAlex GeeHai I. WangFanmiao KongMichael ClarkeMatthew EdmondsonJack HartJames N. O’SheaWojciech StawskiJonathan BaughAkimitsu NaritaAlex SaywellMischa BonnKlaus MüllenLapo BoganiHarry L. Anderson doi:10.1038/s41557-024-01477-1 Nature Chemistry, Published online: 2024-03-08; | doi:10.1038/s41557-024-01477-1 2024-03-08 Nature Chemistry 10.1038/s41557-024-01477-1 https://www.nature.com/articles/s41557-024-01477-1
<![CDATA[Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions]]> https://www.nature.com/articles/s41557-024-01476-2 Nature Chemistry, Published online: 08 March 2024; doi:10.1038/s41557-024-01476-2

Although hydrogels with complex, heterogeneous and reconfigurable structures are promising materials for use in intelligent systems, fabricating such hydrogels is challenging. Now it has been shown that they can be fabricated by reversibly gluing different hydrogel units using a photocontrolled metallopolymer adhesive. This method can be used to design hydrogels with customized functions.]]>
Jiahui LiuYun-Shuai HuangYazhi LiuDachuan ZhangKaloian KoynovHans-Jürgen ButtSi Wu doi:10.1038/s41557-024-01476-2 Nature Chemistry, Published online: 2024-03-08; | doi:10.1038/s41557-024-01476-2 2024-03-08 Nature Chemistry 10.1038/s41557-024-01476-2 https://www.nature.com/articles/s41557-024-01476-2
<![CDATA[Exploring the frontiers of condensed-phase chemistry with a general reactive machine learning potential]]> https://www.nature.com/articles/s41557-023-01427-3 Nature Chemistry, Published online: 07 March 2024; doi:10.1038/s41557-023-01427-3

Atomistic simulations have a broad range of applications from drug design to materials discovery. Machine learning interatomic potentials (MLIPs) have become an efficient alternative to computationally expensive ab initio simulations. Now a general reactive MLIP (called ANI-1xnr) has been developed and validated against a broad range of condensed-phase reactive systems.]]>
Shuhao ZhangMałgorzata Z. MakośRyan B. JadrichElfi KrakaKipton BarrosBenjamin T. NebgenSergei TretiakOlexandr IsayevNicholas LubbersRichard A. MesserlyJustin S. Smith doi:10.1038/s41557-023-01427-3 Nature Chemistry, Published online: 2024-03-07; | doi:10.1038/s41557-023-01427-3 2024-03-07 Nature Chemistry 10.1038/s41557-023-01427-3 https://www.nature.com/articles/s41557-023-01427-3
<![CDATA[The importance of community as a pre-tenure faculty member]]> https://www.nature.com/articles/s41557-024-01474-4 Nature Chemistry, Published online: 06 March 2024; doi:10.1038/s41557-024-01474-4

Becoming an assistant professor brings with it several challenges, one of which is developing new relationships that can be professionally and personally beneficial. Shira Joudan reflects on getting to know people at a new institution, having different types of relationships, and how they help with happiness and success.]]>
Shira Joudan doi:10.1038/s41557-024-01474-4 Nature Chemistry, Published online: 2024-03-06; | doi:10.1038/s41557-024-01474-4 2024-03-06 Nature Chemistry 10.1038/s41557-024-01474-4 https://www.nature.com/articles/s41557-024-01474-4
<![CDATA[A blueprint for catalysis]]> https://www.nature.com/articles/s41557-024-01438-8 Nature Chemistry, Published online: 06 March 2024; doi:10.1038/s41557-024-01438-8

Ciro Romano, Jack I. Mansell, and David J. Procter have explored the versatility and selectivity of samarium diiodide, and its use as a radical relay catalyst.]]>
Ciro RomanoJack I. MansellDavid J. Procter doi:10.1038/s41557-024-01438-8 Nature Chemistry, Published online: 2024-03-06; | doi:10.1038/s41557-024-01438-8 2024-03-06 Nature Chemistry 10.1038/s41557-024-01438-8 https://www.nature.com/articles/s41557-024-01438-8