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<channel>
	<title>Nature News Blog</title>
	
	<link>http://blogs.nature.com/news</link>
	<description>Breaking news from the world of science</description>
	<lastBuildDate>Thu, 17 May 2012 15:26:05 +0000</lastBuildDate>
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		<title>Council questions $20 million award by Texas cancer institute</title>
		<link>http://feeds.nature.com/~r/news/rss/newsblog/~3/jBpeZJWs1Kc/council-questions-20-million-award-by-texas-cancer-institute.html</link>
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		<pubDate>Thu, 17 May 2012 15:19:25 +0000</pubDate>
		<dc:creator>Helen Thompson</dc:creator>
				<category><![CDATA[Policy]]></category>

		<guid isPermaLink="false">http://blogs.nature.com/news/?p=18476</guid>
		<description><![CDATA[On the heels of Nobel laureate Al Gilman’s announcement that he plans to resign as the chief scientific officer of the US$3 billion Cancer Research Institute of Texas (CPRIT) and the leaking of his resignation letter which raised concerns about the Institute’s peer review process, similar concerns and supporting details are now trickling out from the independent group of scientists that evaluates CPRIT’s research grant applications.&#160; <a href="http://blogs.nature.com/news/2012/05/council-questions-20-million-award-by-texas-cancer-institute.html#wpn-more-18476" class="more-link">Read more</a>]]></description>
			<content:encoded><![CDATA[<p><a class="wpn-image-link" href="http://blogs.nature.com/news/files/2012/05/CPRIT-Logo300.jpg"><img class="wpn-alignright wpn-size-full wp-image-18506 wpn-image" title="CPRIT-Logo300" src="http://blogs.nature.com/news/files/2012/05/CPRIT-Logo300.jpg" alt="" width="300" height="138"/></a>On the heels of Nobel laureate Al Gilman’s announcement that he plans to resign as the chief scientific officer of the US$3 billion Cancer Research Institute of Texas (CPRIT) and the leaking of his resignation letter which <a href="http://blogs.nature.com/news/2012/05/texas-resignation-puts-peer-review-under-microscope.html">raised concerns about the Institute’s peer review process</a>, similar concerns and supporting details are now trickling out from the independent group of scientists that evaluates CPRIT’s research grant applications.</p>
<p title="letter">In a <a href="http://blogs.nature.com/news/files/2012/05/SRC-Letter-CRPIT-Gilman1.pdf">letter</a> dated 14 May, the organization’s scientific review council, chaired by Phillip Sharp of the Massachusetts Institute of Technology, criticize actions taken by the CPRIT management and Oversight Committee — actions which they say are “inconsistent” with statements by CPRIT’s executive director William Gimson defending the integrity of the Institute’s peer review system.  The letter also reiterates the council’s faith in Gilman. In his 8 May resignation letter, Gilman had expressed concerns about CPRIT maintaining a “functional peer review system”.</p>
<p>Gilman told <em>Nature</em> in an email that he believes both letters address “the same basic issues.”</p>
<p>Among the most damning of the council’s concerns is their assertion that they were not consulted about a $20 million ‘incubator’ award  — the largest ever made by CPRIT — that went to Rice University and the University of Texas’s MD Anderson Cancer Center both in Houston. Although the MD Anderson Center is slated to receive $18 million from the award, the council found their proposal too short (only 6.5 pages), too last-minute (it was approved three weeks after submission), and lacking in scientific detail.</p>
<p>“We will be viewed to have approved this award, and the failure to include us in the process calls into question our roles and the integrity of the review program in general. More importantly, this by-pass is inherently unfair to every scientist in Texas who participates in the CPRIT program,” the review council writes.</p>
<p>Incubator grants — to fund programs and services aimed at commercializing new products for cancer diagnosis, treatment, and prevention — are not defined by CPRIT as requiring scientific peer review. But, the council argues that the activities laid out in MD Anderson’s proposal sound like research. Additionally, “no product candidates were mentioned,” said the letter, “Nor is a company involved.” This marked the first time CPRIT has issued an award in this grant category.</p>
<p>“It is clear that the rules surrounding submission, evaluation, and funding of incubators must be clarified,” Gimson said in a statement. “It is my intent to address the concerns that have arisen about the commercialization review process by soliciting input from CPRIT’s stakeholders.”</p>
<p>The review council also criticizes CPRIT’s oversight committee for putting seven multi-investigator research applications that the review council recommended for funding on hold. The letter alleges this was done because of opposition from certain committee members to a significant amount of the funding going to UT Southwestern Medical School in Dallas where Gilman once served as Dean. The review council write that this amounts to an unfounded accusation of bias on the part of both the council and Gilman, which they “vigorously deny.”</p>
<p>Gimson said that the decision was due to timing and budget issues and confirmed that all seven projects are up for consideration at a meeting of the Oversight Committee scheduled for 26 July. In his resignation letter, Gilman suggests that he wants to remain in his role through the summer in part to prevent ”negative decisions” about funding from being made at the same meeting.</p><img src="http://feeds.feedburner.com/~r/news/rss/newsblog/~4/jBpeZJWs1Kc" height="1" width="1"/>]]></content:encoded>
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		<title>French research minister appointed</title>
		<link>http://feeds.nature.com/~r/news/rss/newsblog/~3/c9leSLib4Ng/french-research-minister-appointed.html</link>
		<comments>http://blogs.nature.com/news/2012/05/french-research-minister-appointed.html#comments</comments>
		<pubDate>Thu, 17 May 2012 10:49:34 +0000</pubDate>
		<dc:creator>Declan Butler</dc:creator>
				<category><![CDATA[Policy]]></category>
		<category><![CDATA[Uncategorized]]></category>

		<guid isPermaLink="false">http://blogs.nature.com/news/?p=18488</guid>
		<description><![CDATA[Geneviève Fioraso, deputy mayor of Grenoble, and a Socialist member of the National Assembly (the French parliament), representing the Isère constituency, has been appointed minister of higher education and research in the first goverment of French president François Hollande and prime minister Jean-Marc Ayrault. Fioraso is no stranger to research and innovation issues, which has been her speciality both as a member of parliament, and as deputy mayor of Grenoble, while she is also a member of the Parliamentary Office for the Evaluation of Scientific and Technological Choices. Most recently, she was rapporteur of the office’s February report on the challenges of synthetic biology. She was also part of the group of advisers on innovation in François Hollande’s election campaign team.&#160; <a href="http://blogs.nature.com/news/2012/05/french-research-minister-appointed.html#wpn-more-18488" class="more-link">Read more</a>]]></description>
			<content:encoded><![CDATA[<p><a class="wpn-image-link" href="http://blogs.nature.com/news/files/2012/05/GenevieveFioraso1-295x300.jpg"><img class="wpn-alignright wpn-size-full wp-image-18490 wpn-image" title="GenevieveFioraso1-295x300" src="http://blogs.nature.com/news/files/2012/05/GenevieveFioraso1-295x300.jpg" alt="" width="295" height="300"/></a>Geneviève Fioraso, deputy mayor of Grenoble, and a Socialist member of the National Assembly (the French parliament), representing the Isère constituency, has been appointed minister of higher education and research in the first goverment of French president François Hollande and prime minister Jean-Marc Ayrault. Fioraso is no stranger to research and innovation issues, which has been her speciality both as a member of parliament, and as deputy mayor of Grenoble, while she is also a member of the <a href="http://www.assemblee-nationale.fr/commissions/opecst-index.asp">Parliamentary Office for the Evaluation of Scientific and Technological Choices</a>. Most recently, she was rapporteur of the office’s February <a href="http://www.assemblee-nationale.fr/13/pdf/rap-off/i4354.pdf">report</a> on the challenges of synthetic biology. She was also part of the group of advisers on innovation in François Hollande’s election campaign team.</p>
<p>Fioraso, who is 57 years old, has had a diverse career. Starting out as a lecturer in English and economics, she took a post at the Grenoble city hall in 1979, and became a parliamentary assistant in 1983. In 1989, she took on a management role at the high-tech start-up <a href="http://www.corys.fr/">Corys</a>, where she worked on the safety of nuclear and coal-fired power plants. In 1995, she became head of the office of Grenoble’s deputy mayor, Michel Destot, and in the early 2000′s worked as a marketing executive for France Telecom in emerging social and health applications. Elected to parliament in 2007, she is also chief executive officer of <a href="http://minatec-entreprises.fr/Presentation">Sem Minatec Entreprises</a>, the business incubator wing of <a href="http://www.minatec.org/">Minatec</a>, the renowned Grenoble innovation campus for nanotechnology and electronics, which has some 2400 researchers, 1200 students and 600 industrial staff.</p>
<p>Fioraso is one of 17 women among the 34 ministers nominated to the new government. This parity, promised by Hollande, is a first for France. The new government may undergo a reshuffle after the upcoming parliamentary elections, however, the first round of which will be held on 10 June with the final round being held on 17 June. For the full government line-up see the newspaper Le Monde’s <a href="http://www.lemonde.fr/election-presidentielle-2012/article/2012/05/16/le-gouvernement-de-jean-marc-ayrault_1702528_1471069.html">summary</a>.</p>
<p>Other links: Fioraso’s <a href="http://www.genevieve-fioraso.com/">blog</a> and <a href="http://www.assemblee-nationale.fr/13/tribun/fiches_id/332364.asp ">page</a> at the National Assembly.</p>
<p>Nature’s Q&amp;A’s with Nicolas Sarkozy and François Hollande in the run up to the presidential election – “<a href="http://www.nature.com/news/a-question-of-science-1.10461">A question of science</a>.”</p><img src="http://feeds.feedburner.com/~r/news/rss/newsblog/~4/c9leSLib4Ng" height="1" width="1"/>]]></content:encoded>
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		<title>Earth overburdened by soaring consumption, says WWF report</title>
		<link>http://feeds.nature.com/~r/news/rss/newsblog/~3/aehhYw_aYaU/earth-overburdened-by-soaring-consumption-says-wwf-report.html</link>
		<comments>http://blogs.nature.com/news/2012/05/earth-overburdened-by-soaring-consumption-says-wwf-report.html#comments</comments>
		<pubDate>Wed, 16 May 2012 16:48:15 +0000</pubDate>
		<dc:creator>Mark Peplow</dc:creator>
				<category><![CDATA[Earth, environment & ecology]]></category>

		<guid isPermaLink="false">http://blogs.nature.com/news/?p=18470</guid>
		<description><![CDATA[Orbiting high above the Earth inside the International Space Station, an astronaut issued a grim report card on the state of the planet yesterday, describing current levels of resource consumption as 50 percent higher than the world can sustainably maintain.&#160; <a href="http://blogs.nature.com/news/2012/05/earth-overburdened-by-soaring-consumption-says-wwf-report.html#wpn-more-18470" class="more-link">Read more</a>]]></description>
			<content:encoded><![CDATA[<div id="wpn-attachment_18471" style="width:300px" class="wpn-caption wpn-alignright"><a class="wpn-image-link" href="http://blogs.nature.com/news/files/2012/05/globe_west_540.jpg"><img class="wp-image-18471 wpn-image wpn-" title="globe_west_540" src="http://blogs.nature.com/news/files/2012/05/globe_west_540-300x300.jpg" alt="" width="300" height="300"/></a><div class="wpn-caption-text"><p class="wpn-caption">The world is not enough ... </p><p class="wpn-credit">NASA</p></div>
			</div>
<p><em>Posted on behalf of Katherine Rowland</em></p>
<p>Orbiting high above the Earth inside the International Space Station, an astronaut issued a grim report card on the state of the planet yesterday, describing current levels of resource consumption as 50 percent higher than the world can sustainably maintain.</p>
<p>In a recorded message, Andre Kuipers of the European Space Agency offered a unique view of the planet he circles 16 times each day. “From up here I can see humanity’s footprint, including forest fires, air pollution and erosion,” he said, launching the <a href=" http://awsassets.panda.org/downloads/lpr_2012_final_120507.pdf">World Wildlife Fund’s Living Planet Report for 2012</a>.</p>
<p>The biennial audit, produced in collaboration with the Zoological Society of London and the Global Footprint Network, projects that by 2030 humanity will require the equivalent of two planets to sustain current levels of population growth and resource depletion. “We are living as if we have an extra planet at our disposal,” writes Jim Leape, director general of WWF International, in the report. “We are using 50 percent more resources than the Earth can provide, and unless we change course that number will grow very fast.”</p>
<p>The report monitored ecosystem health by tracking 9,000 populations of more than 2,600 species of mammals, birds, reptiles, amphibians and fish. The findings indicate that global biodiversity had decreased by nearly 30 percent since 1970, and by as much as 60 percent in the tropics.</p>
<p>According to the report, the precipitous losses in tropical regions point to a “potentially catastrophic” gap between the ecological footprint of rich and poor nations. By the study’s measures, if everyone on the planet lived like an average person in the United States, four Earths would be required to replenish the annual demand on natural resources. The United States ranks as the country with the fifth-largest per-capita resource footprint, trailing Qatar, Kuwait, United Arab Emirates and Denmark.</p>
<p>And the disparity between rich and poor nations has been increasing, according to the report’s footprint index, which evaluates resource consumption in relation to biocapacity, or the ability to renew resources and absorb CO<sub>2</sub> emissions.</p>
<p>This trend is driven by high-income countries subsidizing their economic growth on the backs of developing nations, says engineer Gemma Cranston, lead scientist at the Global Footprint Network in Geneva. She argues that the consumption demands of rich nations encourage poor countries to plunder their resource wealth for export.</p>
<p>The report – the eighth of its kind – comes five weeks before the United Nations Conference on Sustainable Development in Rio de Janeiro. Cranston says policy makers will there have an opportunity to forge a new trajectory for economic growth. “High-income countries can help low-income countries set up systems that allow for gains in social wellbeing that don’t come at the expense of ecological harm.”</p>
<p>But Colin Butfield, head of campaigns at WWF UK, is doubtful the summit will result in the level of international commitment necessary to halt “the alarming momentum of environmental damage”. Despite the international conventions signed since the original Rio Summit in 1992, biodiversity losses and CO<sub>2</sub>emissions have accelerated. “20 years on and the overall direction of travel has gotten worse,” he says. “And that direction is pretty terrifying.”</p><img src="http://feeds.feedburner.com/~r/news/rss/newsblog/~4/aehhYw_aYaU" height="1" width="1"/>]]></content:encoded>
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		<title>Montenegrin academicians at loggerheads</title>
		<link>http://feeds.nature.com/~r/news/rss/newsblog/~3/bVTWTAs5LVk/montenegrin-academicians-at-loggerheads.html</link>
		<comments>http://blogs.nature.com/news/2012/05/montenegrin-academicians-at-loggerheads.html#comments</comments>
		<pubDate>Wed, 16 May 2012 16:36:14 +0000</pubDate>
		<dc:creator>Mark Peplow</dc:creator>
				<category><![CDATA[Lab life]]></category>
		<category><![CDATA[Policy]]></category>

		<guid isPermaLink="false">http://blogs.nature.com/news/?p=18459</guid>
		<description><![CDATA[Members of Montenegro’s unofficial science academy, the Doclean Academy of Sciences and Arts (DANU), got a nasty surprise this week.&#160; <a href="http://blogs.nature.com/news/2012/05/montenegrin-academicians-at-loggerheads.html#wpn-more-18459" class="more-link">Read more</a>]]></description>
			<content:encoded><![CDATA[<p><em>Posted on behalf of Mico Tatalovic</em></p>
<p>Members of Montenegro&#8217;s unofficial science academy, the Doclean Academy of Sciences and Arts (DANU), got a nasty surprise this week.</p>
<p>In March, the country’s parliament had <a href="http://www.skupstina.me/cms/site_data/DOC24/749/zakon-749.pdf">mandated</a> that DANU should merge with the official academy, the Montenegrin Academy of Science and Arts (CANU), in an effort to unite the country&#8217;s scientific potential. The two academies have historically been divided along political and ideological lines.</p>
<p>But on Monday 14 May, only five out of twenty-nine DANU members were <a href="http://www.pobjeda.me/2012/05/15/canu-verifikovala-clanstvo-petorici-akademika-danu/">elected to CANU</a> — and even those only as associate and foreign members.</p>
<p>DANU was established in 1998 as part of the Montenegrin national renaissances that led to its independence from Serbia in 2006. CANU was set up in 1971, when Montenegro was one of the republics in former Yugoslavia.</p>
<p>CANU members have opposed the merger — which effectively forces them to admit verified DANU members to their academy — arguing that it undermines their autonomy from government. CANU challenged the law at the constitutional court, and also instituted a new procedure which puts members of DANU through a rigorous selection process instead of simply admitting them, as the law mandates.</p>
<p>Both DANU and the government’s science ministry have deemed this new procedure illegal, and this case is also being fought in the constitutional court. DANU members will probably have to wait for rulings from both of these cases to know whether or not they can join the country&#8217;s official academy.</p>
<p>&#8220;Decisions made at the CANU assembly on 14 May will not be valid, because their procedures do not call for verification of DANU members, but instead an election of new members,&#8221; Milena Milunović, an aide at the science ministry <a href="http://www.pobjeda.me/2012/05/01/ministarstvo-nauke-odluke-skupstine-canu-nece-biti-validne/ ">told <em>Pobjeda</em> newspaper</a> earlier this month. The ministry declined to comment further until the court ruling is out.</p>
<p>DANU issued a statement calling CANU&#8217;s most recent decision &#8220;illegitimate and against the law&#8221;. Meanwhile, CANU spokesperson Marina Vukičević told <em>Nature</em> that the election of DANU members was done according to a procedure laid down in the new law, and not according to CANU&#8217;s disputed new procedure, and is therefore legitimate.</p>
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		<title>R&amp;D Scoreboard is gone for good</title>
		<link>http://feeds.nature.com/~r/news/rss/newsblog/~3/P6qTlaFPGwc/rd-scoreboard-is-gone-for-good.html</link>
		<comments>http://blogs.nature.com/news/2012/05/rd-scoreboard-is-gone-for-good.html#comments</comments>
		<pubDate>Wed, 16 May 2012 16:13:32 +0000</pubDate>
		<dc:creator>Brian Owens</dc:creator>
				<category><![CDATA[Policy]]></category>

		<guid isPermaLink="false">http://blogs.nature.com/news/?p=18465</guid>
		<description><![CDATA[The UK government is not going to reinstate its R&#038;D Scoreboard, which analysed the R&#038;D investment by the country’s top 1,000 research-active businesses and investment by the top 1,000 global companies in the UK. The last edition was produced in November 2010, but earlier this year the government considered reviving the annual report. According to the Campaign for Science and Engineering (CaSE), this has now been ruled out.&#160; <a href="http://blogs.nature.com/news/2012/05/rd-scoreboard-is-gone-for-good.html#wpn-more-18465" class="more-link">Read more</a>]]></description>
			<content:encoded><![CDATA[<p><em>Posted on behalf of Alice Lighton.</em></p>
<p>The UK government is not going to reinstate its R&amp;D Scoreboard, which analysed the R&amp;D investment by the country’s top 1,000 research-active businesses and investment by the top 1,000 global companies in the UK. The last edition was produced in November 2010, but earlier this year the government <a href="http://www.theyworkforyou.com/wrans/?id=2012-03-27a.102208.h">considered reviving</a> the annual report. According to the Campaign for Science and Engineering (CaSE), this has now been ruled out.</p>
<p>The decision has been met with disappointment. Imran Khan , director of CaSE, wrote on <a href="http://sciencecampaign.org.uk/?p=9906">his blog</a>, “When we’re trying to increase private-sector investment it’s important that we can see whether the Government’s strategy is working or not &#8230; we’re both surprised and disappointed that they have confirmed they won’t be reversing a hastily-taken and short-sighted decision.”</p>
<p>The scoreboard provided information on innovation across a wide range of sectors and allowed to UK to be compared to other countries. It provided a definitive and accurate measure of the state of R&amp;D; its figures were almost never revised.</p>
<p>CaSE claims budgetary concerns are the reason the Scoreboard has been binned. Announcing the end in 2010, science minister David Willets blamed &#8220;<a href="http://webarchive.nationalarchives.gov.uk/20101208170217/http:/www.innovation.gov.uk/rd_scoreboard/">unprecedented financial pressures</a>&#8220;. The report cost around £410,000 to produce each year.</p>
<p>The UK has several other methods of measuring what businesses spend on R&amp;D, though none are as rigorous as the Scoreboard. The bi-annual UK Innovation Survey is based on voluntary responses from businesses with 10 or more employees. The Business Enterprise Research and Development and Gross Domestic Expenditure on Research and Development surveys (<a href="http://www.statistics.gov.uk/hub/business-energy/businesses/research-and-development">BERD and GERD</a>) are based on the responses of 4,600 businesses, and are submitted to the EU and OECD for comparisons with other countries.</p>
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		<title>Disappearing hand trick wins best illusion of 2012</title>
		<link>http://feeds.nature.com/~r/news/rss/newsblog/~3/oplc6V4KSRI/disappearing-hand-trick-wins-best-illusion-of-2012.html</link>
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		<pubDate>Wed, 16 May 2012 15:40:06 +0000</pubDate>
		<dc:creator>Brian Owens</dc:creator>
				<category><![CDATA[Neuroscience]]></category>

		<guid isPermaLink="false">http://blogs.nature.com/news/?p=18460</guid>
		<description><![CDATA[Watch where you put your hands, because Roger Newport of the University of Nottingham knows how to fool a brain into thinking they have vanished. This sleight of mind is so compelling that it has officially been crowned the best illusion in the world.&#160; <a href="http://blogs.nature.com/news/2012/05/disappearing-hand-trick-wins-best-illusion-of-2012.html#wpn-more-18460" class="more-link">Read more</a>]]></description>
			<content:encoded><![CDATA[<p><em>Posted on behalf of Julian De Freitas.</em></p>
<p>Watch where you put your hands, because Roger Newport of the University of Nottingham knows how to fool a brain into thinking they have vanished. This sleight of mind is so compelling that it has officially been crowned the best illusion in the world.</p>
<p>“The illusions this year were particularly spectacular”, says Stephen Macknik, judge moderator for the 8thAnnual Best Illusion of the Year contest, which took place at the annual meeting of the Vision Sciences Society in Florida yesterday. The 10 best illusions from 59 entries were unveiled in a concert hall packed with vision scientists from across the globe, who voted for the final winners.</p>
<p><iframe src="http://www.youtube.com/embed/Qcm0_QPhLe4?rel=0" frameborder="0" width="420" height="315"/></p>
<p>Newport’s was the only tactile illusion. As shown in the video, a participant places both hands into a closed box, and then tries to keep them still while being shown a video of them. The video is manipulated so that the hands appear to drift slowly toward each other; in an attempt to counteract this drift, the participant moves her hands further away from each other. Eventually, she has moved them a fair distance apart without even noticing having done so, since the video continues to display an image of her hands close to each other.<span id="wpn-more-18460"/></p>
<p>The image of her right hand then disappears completely, and the experimenter asks her to grab it with her left hand. To her astonishment, her right hand is no longer where she thought it was.</p>
<p>Newport explains, “We created this illusion by separating the different senses. It’s the combined loss of vision and touch that creates an experience that the hand is missing. It’s very striking, and works for everybody who does it.” Newport also thinks that the discovery might end up having applications outside of the lab, such as for sufferers of osteoarthritis: “It could change the very way we perceive pain.”</p>
<p>Newport was up against some tough competition. Second place was taken by an illusion that recently went viral on YouTube: ‘When pretty girls turn ugly: the flashed face distortion effect.’ In this video, pairs of different faces are sequentially flashed on the screen for brief periods. Although you don’t notice anything unusual if you stare at any individual face, a very strange effect occurs if you fix your eyes between the faces — <a href="http://illusioncontest.neuralcorrelate.com/2012/when-pretty-girls-turn-ugly-the-flashed-face-distortion-effect/">they suddenly appear highly deformed and grotesque</a>. At the competition yesterday, Matthew Thompson from the University of Queensland in Australia also unveiled a never-before-seen version of the illusion that uses celebrity faces, much to the delight of the audience.</p>
<p>The explanation for the flashed face distortion effect remains unclear, but that’s not uncommon according to Susanna Martinez-Conde, president of the Neural Correlate Society, which hosts the competition. “These are the best illusions of the year, so they’re very new by definition. You’re going to know the phenomenology first, and the neural underpinnings second. Typically, we don’t know why these illusions work in the brain. We may have theories, but the experiments have not been done, because it’s too early. This is really at the cutting edge.”</p>
<p><em>Video © 2012 Roger Newport, Helen Gilpin and Catherine Preston</em></p><img src="http://feeds.feedburner.com/~r/news/rss/newsblog/~4/oplc6V4KSRI" height="1" width="1"/>]]></content:encoded>
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		<title>World’s science funders announce Global Research Council</title>
		<link>http://feeds.nature.com/~r/news/rss/newsblog/~3/BNXDcz3i8rE/worlds-science-funders-announce-global-research-council.html</link>
		<comments>http://blogs.nature.com/news/2012/05/worlds-science-funders-announce-global-research-council.html#comments</comments>
		<pubDate>Wed, 16 May 2012 01:46:02 +0000</pubDate>
		<dc:creator>Richard Van Noorden</dc:creator>
				<category><![CDATA[Policy]]></category>

		<guid isPermaLink="false">http://blogs.nature.com/news/?p=18436</guid>
		<description><![CDATA[After a string of regional preparations and a three-day summit at the headquarters of the US National Science Foundation (NSF) in Washington DC, the leaders of some 50 research agencies yesterday announced the establishment of the Global Research Council (GRC), a forum which will examine issues important to science funding agencies worldwide.&#160; <a href="http://blogs.nature.com/news/2012/05/worlds-science-funders-announce-global-research-council.html#wpn-more-18436" class="more-link">Read more</a>]]></description>
			<content:encoded><![CDATA[<p>After a string of regional preparations and a three-day summit at the headquarters of the US National Science Foundation (NSF) in Washington DC, the <a href="http://www.nsf.gov/news/newsmedia/globalsummit/biographical_snapshots.pdf">leaders of some 50 research agencies</a> yesterday announced the establishment of the <a href="http://www.globalresearchcouncil.org/">Global Research Council</a> (GRC), a forum that will examine issues important to science-funding agencies worldwide.</p>
<p>At a press conference on 15 May (<a href="http://www.nsf.gov/news/news_videos.jsp?cntn_id=124178&amp;media_id=72475&amp;org=NSF">webcast</a>), NSF head Subra Suresh said that the GRC was not just a place to discuss shared goals and aspirations, but was “the first step toward a more unified approach to the scientific process.” (In an <a href="http://www.nsf.gov/news/newsmedia/globalsummit/science_editorial.pdf">editorial</a> in <em>Science</em> last August, he argued that differing standards for science funding and practice were the “most fundamental barriers to … international collaborations”).</p>
<p>The GRC’s first output is a consensus on <a href="http://www.nsf.gov/news/newsmedia/globalsummit/gs_principles.pdf">six common principles for using merit review (peer review) to assess and fund scientific research projects</a> — including transparency, integrity, impartiality and confidentiality. “For funding agencies, peer review is our bread and butter. We have to pick the best ideas and people in the most transparent and ethical manner,” Suresh says.</p>
<p>Next year, after more regional gatherings, the forum will meet in Berlin, where Germany and Brazil will co-host discussions on research integrity, and on how to promote open access to research data and publications. Participants expect the number of nations involved to double, and six other countries are already hoping to host the council in 2014, Suresh says. Topics to explore then could include the funding of research infrastructure and how best to manage intellectual property.</p>
<p><span id="wpn-more-18436"/></p>
<p>Quite what the GRC will become, no one yet knows. It might blossom into an influential organization that brokers detailed agreement on best practices for managing and conducting research, and promotes collaboration and co-funding between nations.</p>
<p>Suresh says he hopes that if dozens of countries articulate principles for peer review, data sharing, integrity and data access, then these might be adopted by any institution negotiating trans-national research, including universities and private organizations. Other participants in the meeting said that the council could make it easier for heads of research funding worldwide to design multilateral projects. The GRC will not be controlling any funding itself — at least, not for now.</p>
<p>On the other hand, the GRC could just evolve into a useful but limited talking shop, where research agencies agree on broad-brush issues but do little to resolve practical differences. Despite the close links between research agencies across Europe, for example, there’s a large variety in their practices, as a <a href="http://www.nature.com/news/2011/110504/full/473017a.html">detailed study on peer review by the European Science Foundation</a> has revealed. Some of the GRC work was based on this study. “A large variety of practices is to be expected, cherished and celebrated,” Suresh says.</p>
<p>After the first meeting — carefully prepared for by four regional gatherings across the globe — participants were optimistic. For a start, everyone invited turned up (except two people stymied by a cancelled United Airlines flight), noted Suresh — including participants from Egypt, Saudi Arabia and China. And Glaucius Oliva, president of Brazil’s National Council for Scientific and Technological Development (CNPq), noted one potential impact already: the international agreement that peer review should be kept confidential might help his funding agency to hold out against potential freedom-of-information demands under Brazil’s new open-government policies, he said.</p>
<p>To Pär Omling, vice-president of <a href="http://www.scienceeurope.org/">Science Europe</a>, the voluntary and informal trust-building involved in the new forum felt a bit like the start of EUROHORCS, a group made up of the heads of European research councils. “With time that developed — we wanted to start collaborative research programmes — and at the end of the day it turned out we required a more solid organization, which is Science Europe,” he said. “Maybe in the future, we’ll see those same sorts of developments internationally.”</p><img src="http://feeds.feedburner.com/~r/news/rss/newsblog/~4/BNXDcz3i8rE" height="1" width="1"/>]]></content:encoded>
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		<title>Guppies lust after killer orange prawn</title>
		<link>http://feeds.nature.com/~r/news/rss/newsblog/~3/W834Ngyb08M/guppies-lust-after-killer-orange-prawn.html</link>
		<comments>http://blogs.nature.com/news/2012/05/guppies-lust-after-killer-orange-prawn.html#comments</comments>
		<pubDate>Wed, 16 May 2012 00:01:19 +0000</pubDate>
		<dc:creator>Brian Owens</dc:creator>
				<category><![CDATA[Biology & Biotechnology]]></category>

		<guid isPermaLink="false">http://blogs.nature.com/news/?p=18369</guid>
		<description><![CDATA[A murky-brown prawn that lives off the coast of Trinidad has evolved orange spots on its pincers to tempt local guppies. The fish mistake the markings for both food and a potential mate, and unwittingly become the prawn’s next meal.&#160; <a href="http://blogs.nature.com/news/2012/05/guppies-lust-after-killer-orange-prawn.html#wpn-more-18369" class="more-link">Read more</a>]]></description>
			<content:encoded><![CDATA[<p><em>Posted on behalf of Alice Lighton.</em></p>
<div id="wpn-attachment_18377" style="width:300px" class="wpn-caption wpn-alignright"><a class="wpn-image-link" href="http://blogs.nature.com/news/files/2012/05/DeSerrano.jpg"><img class="wpn-size-medium wp-image-18377 wpn-image" title="prawn" src="http://blogs.nature.com/news/files/2012/05/DeSerrano-300x226.jpg" alt="" width="300" height="226"/></a><div class="wpn-caption-text"><p class="wpn-caption">The model prawn used in the experiment, with female guppy at bottom left.</p><p class="wpn-credit">A. De Serrano</p></div>
			</div>
<p>A murky-brown prawn that lives off the coast of Trinidad has evolved orange spots on its pincers to tempt local guppies. The fish mistake the markings for both food and a potential mate, and unwittingly become the prawn’s next meal.</p>
<p>Researchers placed a model of a <em>Macrobrachium crenulatum</em> prawn into a tank with female Trinidadian guppies, who were understandably wary of its head and claw areaa. But when the prawn’s pincers were decorated with orange spots, as they are in the wild, the fish couldn’t resist taking a closer look.</p>
<p>The experiment, published today in <em>Proceedings of the Royal Society B</em>, didn’t show whether the fish mistook the prawn for food or a male guppy. Trinidadian guppies originally evolved orange markings to attract mates, because of the resemblance to nutritious orange fruits that fall into the coastal waters. The prawns appear to have latched onto the same trick, and are now convincing enough that they can catch the guppies’ attention.</p>
<p>“The guppies pecked at the prawn, suggesting they thought it was a food source, but then it’s all linked back together,” says Cameron Weadick, a member of the research team at the University of Toronto in Ontario.</p>
<p>This sort of trickery is seen throughout the animal kingdom. The larvae of one species of North American mussel are parasitic and must be eaten to survive. They therefore group together into the shape of a minnow until they are ingested by a larger fish. Similarly, female <em>Photuris</em> fireflies use their light to attract males of a different genus, which they then eat. However, the authors of the guppy paper believe that <em>M. crenulatum</em> is the only species that takes advantage of both foraging and sexual desire.</p>
<p>The researchers were unable to transport a live <em>M. crenulatum</em> from Trinidad to Canada, so as well as using a model of a prawn, they attempted to disguise a crayfish using orange nail varnish. The crayfish acted as a predator, and grabbed at the fish with its pincers, but the guppies were not fooled. “Guppies are probably clued into a lot of things — movement patterns, smells, not just colour,” says Weadick.</p>
<p>There is no guarantee the prawn’s disguise will continue to work. <em>M. crenulatum</em>’s colouring may one day provide enough evolutionary pressure that female guppies associate orange with danger, rather than desire.</p><img src="http://feeds.feedburner.com/~r/news/rss/newsblog/~4/W834Ngyb08M" height="1" width="1"/>]]></content:encoded>
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		<title>Global vaccine plan draws criticism</title>
		<link>http://feeds.nature.com/~r/news/rss/newsblog/~3/VUHE6neELFc/doctors-without-borders-lambastes-global-vaccine-plan.html</link>
		<comments>http://blogs.nature.com/news/2012/05/doctors-without-borders-lambastes-global-vaccine-plan.html#comments</comments>
		<pubDate>Tue, 15 May 2012 20:56:56 +0000</pubDate>
		<dc:creator>Amy Maxmen</dc:creator>
				<category><![CDATA[Health and medicine]]></category>

		<guid isPermaLink="false">http://blogs.nature.com/news/?p=18408</guid>
		<description><![CDATA[Doctors without Borders calls a $10 billion dollar vaccine initiative, supported by the Bill &#038; Melinda Gates Foundation, and the global plan that will implement it, seriously flawed. The humanitarian organization says the plans fail to prioritize the 20% of babies worldwide – some 19 million infants – who never receive basic, life-saving shots.&#160; <a href="http://blogs.nature.com/news/2012/05/doctors-without-borders-lambastes-global-vaccine-plan.html#wpn-more-18408" class="more-link">Read more</a>]]></description>
			<content:encoded><![CDATA[<p><a class="wpn-image-link" href="http://blogs.nature.com/news/files/2012/05/womanbebe300-credit-amaxmen-e1337115268625.jpg"><img class="wpn-alignright wpn-size-medium wp-image-18419 wpn-image" title="womanbebe300-credit-amaxmen" src="http://blogs.nature.com/news/files/2012/05/womanbebe300-credit-amaxmen-e1337115268625-211x300.jpg" alt="" width="211" height="300"/></a>The international humanitarian relief organization Médecins Sans Frontières (MSF), also known as Doctors Without Borders, has <a href="http://www.doctorswithoutborders.org/press/release.cfm?id=6017&amp;cat=press-release">called</a> a US$10-billion dollar vaccination effort seriously flawed.</p>
<p>The Global Vaccine Action Plan (GVAP) was developed by the Bill and Melinda Gates Foundation, among other partners, with the goal of increasing immunization world wide. But MSF says that the plan fails to address the 20% of infants — some 19 million — who never receive basic, life-saving shots.</p>
<p>Rather than pushing for novel vaccines, the plan should focus more concretely on strategies to get existing vaccines to children, MSF says.</p>
<p>The organization is hoping to draw attention to this issue ahead of discussions that will occur next week in Geneva at the <a href="http://www.who.int/mediacentre/events/2012/wha65/en/index.html">2012 World Health Assembly</a>.</p>
<p>“It’s great to have new vaccines, but we need to address the problem of getting what is needed to where it is needed,” says Jane Boggini, a field nurse for MFS.</p>
<p>Misleading statistics account, in part, for why vaccine coverage has fallen to the wayside in the current plan, says Daniel Berman, deputy director of the<a href="http://www.msfaccess.org/"> MSF Access Campaign</a>. “The rhetoric we see is that routine vaccination is working, and now we can just add new vaccines to the mix,” Berman says. Vaccination surveys come up with varying results, he explains. For example, the World Health Organization claims that <a href="http://doctorswithoutborders.org/publications/reports/2012/MSF%20Vaccines%20Report%20THE%20RIGHT%20SHOT%20May%202012%282%29.pdf">82%</a> of children in the poorest countries received their three basic DTP3 (diphtheria, pertussis and tetanus) vaccines in 2011, but Berman says that the numbers are closer to 30% or 40% in many regions.<span id="wpn-more-18408"/></p>
<p>Further, gaps in vaccination fade into the background when global health organizations emphasize only gains made over the past decade, says Berman. The organization would <a href="http://www.doctorswithoutborders.org/press/release.cfm?id=6017&amp;cat=press-release">prefer</a> that world leaders discuss why six of the ten countries listed as having the highest proportion unvaccinated children in 2006 remained at the top in 2010, or why 28 African countries suffered <a href="http://www.cdc.gov/measles/">measles</a> outbreaks in 2010, when a vaccine to prevent the potentially fatal respiratory disease has existed for 40 years.</p>
<p>Last year, Boggini gained first-hand knowledge of what current vaccine campaigns lack when she worked with her MSF colleagues in South Sudan during a measles outbreak. To vaccinate children in rural villages, Boggini says, the team trudged through streams and swamps, carrying food, water, syringes, and vaccines kept in heavy, cooled containers. “Sometimes the water was up to my shoulders,” Boggini says. “We vaccinated 1,500 children, but we had to return before we reached the most remote regions because we could no longer keep the vaccines cold.” As in South Sudan, health workers in the Democratic Republic of Congo, Sierra Leone, Nigeria, India, Pakistan and other countries <a href="http://doctorswithoutborders.org/publications/reports/2012/MSF%20Vaccines%20Report%20THE%20RIGHT%20SHOT%20May%202012%282%29.pdf">struggle</a> to keep vaccines at 3–8° Celsius.</p>
<p>Injections provide another obstacle, as people trained to give shots are in short supply in regions that can’t afford to pay health workers salaries. Thus, MSF says, the global plan should have pushed for ways to reformulate vaccines so that they can be given orally or through nasal sprays. The group adds that the plan also ought to have included a discussion on how quality-assured vaccine manufacturers in India and other developing countries can <a href="http://lb-web1.doctorswithoutborders.org/publications/reports/2012/MSF%20Vaccines%20Report%20THE%20RIGHT%20SHOT%20May%202012%282%29.pdf">help to lower the cost of vaccines</a> so that developing countries’ governments can afford them.</p>
<p>Finally, MSF recommends more research on vaccination schedules. At present, babies must visit health workers four times for the DTP3 and measles vaccines within their first year of life. In industrialized countries, these appointments may seem reasonable. But in the developing world, a hospital visit often requires a walking journey down dirt paths, with multiple children in tow. Berman says that an MSF research group is now assessing the efficacy of a single pneumonia vaccine given anytime before a child reaches 14 years old, rather than three doses at specified dates. “These are the types of studies that need to be in the global plan, but they will not be in the plan if industry has too much say,” he says, adding, “that is against their financial interest.”</p>
<p><em>Photo credit: Amy Maxmen</em></p><img src="http://feeds.feedburner.com/~r/news/rss/newsblog/~4/VUHE6neELFc" height="1" width="1"/>]]></content:encoded>
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		<title>US strategy for Alzheimer’s disease laid out</title>
		<link>http://feeds.nature.com/~r/news/rss/newsblog/~3/w5oLB0Tke-c/us-lays-out-strategy-for-alzheimers-disease.html</link>
		<comments>http://blogs.nature.com/news/2012/05/us-lays-out-strategy-for-alzheimers-disease.html#comments</comments>
		<pubDate>Tue, 15 May 2012 20:29:57 +0000</pubDate>
		<dc:creator>Meredith Wadman</dc:creator>
				<category><![CDATA[Biology & Biotechnology]]></category>
		<category><![CDATA[Health and medicine]]></category>
		<category><![CDATA[Policy]]></category>

		<guid isPermaLink="false">http://blogs.nature.com/news/?p=18395</guid>
		<description><![CDATA[The US government today released its first strategic plan for battling Alzheimer’s Disease, the progressive, incurable dementia that afflicts more than five million Americans.&#160; <a href="http://blogs.nature.com/news/2012/05/us-lays-out-strategy-for-alzheimers-disease.html#wpn-more-18395" class="more-link">Read more</a>]]></description>
			<content:encoded><![CDATA[<p><a class="wpn-image-link" href="http://blogs.nature.com/news/files/2012/05/NatlPlan-spot300.jpg"><img class="wpn-alignright wpn-size-full wp-image-18411 wpn-image" title="NatlPlan-spot300" src="http://blogs.nature.com/news/files/2012/05/NatlPlan-spot300.jpg" alt="" width="300" height="369"/></a><a href="http://www.hhs.gov/news/press/2012pres/05/20120515a.html">The US government today released its first strategic plan for battling Alzheimer’s disease</a>, the progressive, incurable dementia that afflicts more than 5 million Americans.</p>
<p>Speaking at a large Alzheimer’s research summit on the campus of the US National Institutes of Health (NIH), Kathleen Sebelius, the US Secretary of Health and Human Services, called the 59-page <em><a href="http://aspe.hhs.gov/daltcp/napa/NatlPlan.pdf">National Plan to Address Alzheimer’s Disease</a> </em>“a blueprint for building on our research efforts” and “a road map that will help us meet our goal to effectively prevent and treat Alzheimer’s disease by 2025.”</p>
<p>Sebelius also promoted a <a href="http://www.alzheimers.gov/">new website</a> that the department is launching as a “one stop shop” offering resources and support for patients with Alzheimer’s and their families and caregivers.</p>
<p>The plan was mandated by the National Alzheimer’s Project Act, which was signed into law by President Barack Obama in January 2011. The law directed a 25-member advisory committee to come up with the plan, which was released in draft form early this winter.  <a href="http://www.nature.com/news/fleshing-out-the-us-alzheimer-s-strategy-1.9856"><em>Nature</em> published this interview with Ronald Petersen, the Mayo Clinic Alzheimer’s expert</a> who heads the committee, shortly after the draft was released.</p>
<p>Today’s final plan, which deals with quality of care, community support and public awareness — in addition to research — is substantially unchanged from the draft, but that didn’t dampen enthusiasm on the NIH campus.</p>
<p>“We’re very excited about seeing how this exceptional moment can be utilized,” said Francis Collins, the NIH director.</p>
<p>The research elements in the plan are not surprising. They include suggestions that international research be coordinated to avoid duplication; that clinical trials on both prevention and treatment be expanded; and that trials include more ethnic and racial minorities.</p>
<p>Collins fleshed out how the NIH will use the US$50 million in current-year funds that it has redirected to research on Alzheimer’s as part of the administration’s new emphasis on the disease.  He and Sebelius had already announced the 2012 Alzheimer’s money in February, noting, as <em>Nature</em> reported then (see ‘<a href=" http://blogs.nature.com/news/2012/02/graying-us-boosts-alzheimers-research-outlays.html">Graying US boosts Alzheimer’s research</a>‘)  that about $25 million will be used to sequence the genomes and exomes of people afflicted with Alzheimer’s and of unaffected individuals, to identify both risk factors and protective genetic variants.</p>
<p><span id="wpn-more-18395"/>Today, Collins announced that $7.9 million of the remainder will be spent on a five-year clinical trial of 240 participants with mild cognitive impairment and early Alzheimer’s Disease, to see if an insulin nasal spray can improve symptoms of impaired memory and cognition. Conditions such as diabetes, in which the body makes too little insulin or resists its effects, are associated with an increased risk of Alzheimer’s. A promising <a href="http://archneur.jamanetwork.com/article.aspx?volume=69&amp;issue=1&amp;page=29">pilot study published in <em>Archives of Neurology</em> last year showed insulin improving both memory and cognition in affected subjects.</a> The principal investigator for the clinical trial is <a href="http://depts.washington.edu/memorywe/index.php?option=com_content&amp;view=article&amp;id=53&amp;Itemid=63">Suzanne Craft at the University of Washington and the Veterans Affairs Puget Sound Health Care System</a><a href="http://depts.washington.edu/memorywe/index.php?option=com_content&amp;view=article&amp;id=53&amp;Itemid=63"> in Seattle</a>.</p>
<p>The biomedical agency will also contribute $16 million for another, <a href="http://banneralz.org/media/28067/api_prevention_trial_release_5_15_12.pdf">five-year prevention trial in which the anti-amyloid antibody crenezumab will be used to try to prevent Alzheimer’s in young, cognitively healthy members of a large Colombian family</a>.</p>
<p>Members of this family share a rare mutation that triggers Alzheimer’s symptoms in mid-life.  The trial is being run by the Banner Alzheimer’s Institute in Phoenix, Arizona, which is contributing an additional $16 million, by the University of Antioquia in Colombia and by Genentech, which is providing the drug and the balance of funding for the $100 million trial. It will also include a smaller number of US subjects.</p>
<p>What was not discussed today was the $80 million in new Alzheimer’s-research money for 2013 that the administration included in its budget proposal in February. The administration wants the NIH to do the research, but proposed tapping the controversial Public Health Prevention Fund in Sebelius’s office for the money.</p>
<p>That plan is not sitting well with Iowa Democrat Tom Harkin, the chair of the Senate subcommittee that funds the NIH.  As <em>Nature</em> reported in March (see ‘<a href="http://blogs.nature.com/news/2012/03/alzheimers-funding-draws-fire-at-nih-budget-hearing.html">Alzheimer’s funding draws fire at NIH budget hearing</a>‘), Harkin is unhappy at the notion of NIH researchers raiding a fund mandated by the Affordable Care Act to address public-health prevention issues. “I’m a strong supporter of Alzheimer’s research, but this $80 million isn’t happening,” he said.</p>
<p>After today’s announcement, Donald Moulds, the principal deputy assistant secretary in the Office of Planning and Evaluation of the US Department of Health and Human Services, declined to comment directly on Harkin’s remarks.  “We’re very early in the budget conversation for 2013,” he said, adding: “We are absolutely committed to the funding of the $80 million in research in 2013.”</p>
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