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Volume 18 Issue 8, August 2023

Light accelerates colorimetric pathogen detection.

The cover image shows a chamber of a microfluidic device where RNA from lysed viral particles (image left) is rapidly amplified through the action of both the RNA polymerase enzyme (image centre) and the injected electrons from the plasmonic materials (image bottom). The result obtained is both amplified DNA and the generation of protons, which drives the solution colour change towards yellow (image top).

Paper by S. Mahshid

Credit: Ella Marushchenko and Ekaterina Zvorykina (Ella Maru Studio, Inc.). Cover Design by Amie Fernandez.

Editorial

  • Ultrathin ferroelectric materials, including perovskites, hafnium oxides, and van der Waals stacks are of increasing interest because they exhibit properties that are hard to achieve in bulk and because of their suitability for low-power miniaturized devices.

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News & Views

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Research Briefings

  • An automated system that couples microfluidics with plasmonic hot electron injection to accelerate colorimetric detection of DNA and RNA amplification is shown to achieve 95% detection accuracy in human saliva samples. This technique uses different amplification assays for pathogen identification and can differentiate between viral variants and subtypes.

    Research Briefing
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Articles

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Analysis

  • While engineered nanomaterials are relatively new, organisms have been exposed to natural nanoparticles over vast periods of time. Here the authors explore the possibility that common mechanisms of response to nanomaterials may have resulted from a long evolutionary exposure history to natural nano-sized matter.

    • G. del Giudice
    • A. Serra
    • D. Greco
    Analysis Open Access
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