Nature Reviews Genetics
Nature Reviews Genetics is an invaluable source of information in genetics and genomics. The journal’s scope covers the whole breadth of these and related fields, bringing readers cutting-edge Reviews on topics that range from molecular genetics to evolution to systems biology. By publishing Reviews, Progress, Comment, Analysis and Perspective articles, among which are Viewpoints from opinion-leaders, Nature Reviews Genetics provides a balanced and unique perspective of this exciting field which goes well beyond the conventional review, and appeals to students and established scientists alike. All articles are written by carefully chosen leaders in their field and subject to rigorous peer-review, resulting in each issue providing balanced, high-quality and authoritative articles. While experts appreciate the insights and thought-provoking syntheses provided by the high-calibre authors, non-specialists are helped by the glossary definitions, additional background information in the boxes and highlighted references.
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Nature Reviews Genetics
© 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
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Nature Reviews Genetics
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http://feeds.nature.com/nrg/rss/current
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https://www.nature.com/articles/s41576-024-00709-x
Nature Reviews Genetics, Published online: 28 March 2024; doi:10.1038/s41576-024-00709-xIn this Review, the authors compare the characteristics and detection methods of germline and somatic variants. Furthermore, they outline how the interplay between the two types of genetic variation can affect human health.]]>
Zhi YuTim H. H. CoorensMd Mesbah UddinKristin G. ArdlieNiall LennonPradeep Natarajan
doi:10.1038/s41576-024-00709-x
Nature Reviews Genetics, Published online: 2024-03-28; | doi:10.1038/s41576-024-00709-x
2024-03-28
Nature Reviews Genetics
10.1038/s41576-024-00709-x
https://www.nature.com/articles/s41576-024-00709-x
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https://www.nature.com/articles/s41576-024-00728-8
Nature Reviews Genetics, Published online: 27 March 2024; doi:10.1038/s41576-024-00728-8A paper in Nature reports a ‘Z-DNA-anchored’ model for the target specificity of the transcription factor AIRE, involving promoter poising at double-strand breaks.]]>
Kirsty Minton
doi:10.1038/s41576-024-00728-8
Nature Reviews Genetics, Published online: 2024-03-27; | doi:10.1038/s41576-024-00728-8
2024-03-27
Nature Reviews Genetics
10.1038/s41576-024-00728-8
https://www.nature.com/articles/s41576-024-00728-8
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https://www.nature.com/articles/s41576-024-00726-w
Nature Reviews Genetics, Published online: 27 March 2024; doi:10.1038/s41576-024-00726-wReflecting on the importance of short tandem repeats (STRs) in population genetics, Ning Xie highlights a 2023 publication that characterized genome-wide STR variation in global human genomes to expand our understanding of STR genetic diversity within and across populations.]]>
Ning Xie
doi:10.1038/s41576-024-00726-w
Nature Reviews Genetics, Published online: 2024-03-27; | doi:10.1038/s41576-024-00726-w
2024-03-27
Nature Reviews Genetics
10.1038/s41576-024-00726-w
https://www.nature.com/articles/s41576-024-00726-w
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https://www.nature.com/articles/s41576-024-00727-9
Nature Reviews Genetics, Published online: 20 March 2024; doi:10.1038/s41576-024-00727-9A publication in Nature reports the data release of around 245,000 clinical-grade whole-genome sequences as part of the NIH’s All of Us Research Programme. Several companion papers highlight the value of better capturing global genomic diversity.]]>
Linda Koch
doi:10.1038/s41576-024-00727-9
Nature Reviews Genetics, Published online: 2024-03-20; | doi:10.1038/s41576-024-00727-9
2024-03-20
Nature Reviews Genetics
10.1038/s41576-024-00727-9
https://www.nature.com/articles/s41576-024-00727-9
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https://www.nature.com/articles/s41576-024-00724-y
Nature Reviews Genetics, Published online: 19 March 2024; doi:10.1038/s41576-024-00724-yIn this Journal Club, Yoav Ram recalls how he reconciled results from his own research with the reduction principle through the help of a paper published in PNAS by Altenberg et al.]]>
Yoav Ram
doi:10.1038/s41576-024-00724-y
Nature Reviews Genetics, Published online: 2024-03-19; | doi:10.1038/s41576-024-00724-y
2024-03-19
Nature Reviews Genetics
10.1038/s41576-024-00724-y
https://www.nature.com/articles/s41576-024-00724-y
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https://www.nature.com/articles/s41576-024-00710-4
Nature Reviews Genetics, Published online: 18 March 2024; doi:10.1038/s41576-024-00710-4Plants have uniquely adapted to manage endoplasmic reticulum stress triggered by protein misfolding. The authors review the dynamics of gene expression regulation underlying the unfolded protein response in plants, highlighting recent insights provided by systems-level approaches and omics data.]]>
Dae Kwan KoFederica Brandizzi
doi:10.1038/s41576-024-00710-4
Nature Reviews Genetics, Published online: 2024-03-18; | doi:10.1038/s41576-024-00710-4
2024-03-18
Nature Reviews Genetics
10.1038/s41576-024-00710-4
https://www.nature.com/articles/s41576-024-00710-4
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https://www.nature.com/articles/s41576-024-00722-0
Nature Reviews Genetics, Published online: 12 March 2024; doi:10.1038/s41576-024-00722-0A study in Science reports that corn snakes use both PRDM9 and promoter-like features to direct meiotic recombination, indicating that these are not mutually exclusive.]]>
Kirsty Minton
doi:10.1038/s41576-024-00722-0
Nature Reviews Genetics, Published online: 2024-03-12; | doi:10.1038/s41576-024-00722-0
2024-03-12
Nature Reviews Genetics
10.1038/s41576-024-00722-0
https://www.nature.com/articles/s41576-024-00722-0
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https://www.nature.com/articles/s41576-024-00721-1
Nature Reviews Genetics, Published online: 11 March 2024; doi:10.1038/s41576-024-00721-1Bruce Budowle and Antti Sajantila reflect on how short tandem repeats (STRs) became the primary markers of forensic genetics, including for developing investigative leads in criminal cases and humanitarian efforts.]]>
Bruce BudowleAntti Sajantila
doi:10.1038/s41576-024-00721-1
Nature Reviews Genetics, Published online: 2024-03-11; | doi:10.1038/s41576-024-00721-1
2024-03-11
Nature Reviews Genetics
10.1038/s41576-024-00721-1
https://www.nature.com/articles/s41576-024-00721-1