Nature Reviews Gastroenterology and Hepatology - AOP Nature Reviews Gastroenterology & Hepatology provides physicians and academics with authoritative and topical discussions of key developments in the field. http://www.nature.com/nrgastro/current_issue/ Nature Publishing Group en © Nature Publishing Group Nature Reviews Gastroenterology & Hepatology 1759-5045 1759-5053 © Nature Publishing Group permissions@nature.com Nature Reviews Gastroenterology & Hepatology http://www.nature.com/includes/rj_globnavimages/nrgastro_logo.gif http://www.nature.com/nrgastro/ Genetic mechanisms and modifying factors in hereditary hemochromatosis http://feeds.nature.com/~r/nrgastro/rss/aop/~3/TwNNlXlqaVw/nrgastro.2009.201 Hereditary hemochromatosis, or primary iron overload, is one of the most frequent genetic diseases in the world. This Review describes the regulation of iron metabolism and the inherited mutations that cause hereditary hemochromatosis. The author also discusses inherited and environmental modifiers that affect the severity of the disease. Genetic mechanisms and modifying factors in hereditary hemochromatosis

Nature Reviews Gastroenterology & Hepatology. doi:10.1038/nrgastro.2009.201

Author: Günter Weiss

]]> Genetic mechanisms and modifying factors in hereditary hemochromatosis Günter Weiss doi:10.1038/nrgastro.2009.201 Nature Reviews Gastroenterology & Hepatology 2009-11-17 Nature Reviews Gastroenterology & Hepatology 2009-11-17 10.1038/nrgastro.2009.201 http://dx.doi.org/10.1038/nrgastro.2009.201 Review http://dx.doi.org/10.1038/nrgastro.2009.201 Anastomoses of the lower gastrointestinal tract http://feeds.nature.com/~r/nrgastro/rss/aop/~3/9oCGuN5eyyQ/nrgastro.2009.185 Intestinal anastomoses are frequently performed to remove tumors or diseased tissue. They have clear benefits but they can also lead to serious complications such as dehiscences and strictures. This Review discusses the surgical techniques, healing factors and perioperative and postoperative strategies to minimize complications when performing anastomoses of the lower gastrointestinal tract. Anastomoses of the lower gastrointestinal tract

Nature Reviews Gastroenterology & Hepatology. doi:10.1038/nrgastro.2009.185

Authors: Govind Nandakumar, Sharon L. Stein & Fabrizio Michelassi

]]> Anastomoses of the lower gastrointestinal tract Govind Nandakumar Sharon L. Stein Fabrizio Michelassi doi:10.1038/nrgastro.2009.185 Nature Reviews Gastroenterology & Hepatology 2009-11-03 Nature Reviews Gastroenterology & Hepatology 2009-11-03 10.1038/nrgastro.2009.185 http://dx.doi.org/10.1038/nrgastro.2009.185 Review http://dx.doi.org/10.1038/nrgastro.2009.185 Stem cells in gastroenterology and hepatology http://feeds.nature.com/~r/nrgastro/rss/aop/~3/7u4Br9bEUrM/nrgastro.2009.195 Stem cells are primitive, relatively unspecialized cells that can self-renew and are multipotent. In this Review, Quante and Wang discuss potential types of stem cells found within the gastrointestinal tract, the susceptibility of these stem cells for malignant transformation, and their potential for use in restoring tissue function to treat gastrointestinal disorders. Stem cells in gastroenterology and hepatology

Nature Reviews Gastroenterology & Hepatology. doi:10.1038/nrgastro.2009.195

Authors: Michael Quante & Timothy C. Wang

]]> Stem cells in gastroenterology and hepatology Michael Quante Timothy C. Wang doi:10.1038/nrgastro.2009.195 Nature Reviews Gastroenterology & Hepatology 2009-11-03 Nature Reviews Gastroenterology & Hepatology 2009-11-03 10.1038/nrgastro.2009.195 http://dx.doi.org/10.1038/nrgastro.2009.195 Review http://dx.doi.org/10.1038/nrgastro.2009.195 Epidemiology of pancreatic cancer: an overview http://feeds.nature.com/~r/nrgastro/rss/aop/~3/zRK6U0feuas/nrgastro.2009.177 Pancreatic cancer, although infrequent, has an extremely high mortality rate. The epidemiologic features of this rare cancer are still poorly known. In this Review Raimondi and colleagues discuss the environmental, lifestyle and genetic factors that increase or decrease the probability of developing pancreatic cancer and that may explain the different incidence rates observed in distinct subpopulations. Epidemiology of pancreatic cancer: an overview

Nature Reviews Gastroenterology & Hepatology. doi:10.1038/nrgastro.2009.177

Authors: Sara Raimondi, Patrick Maisonneuve & Albert B. Lowenfels

]]> Epidemiology of pancreatic cancer: an overview Sara Raimondi Patrick Maisonneuve Albert B. Lowenfels doi:10.1038/nrgastro.2009.177 Nature Reviews Gastroenterology & Hepatology 2009-10-06 Nature Reviews Gastroenterology & Hepatology 2009-10-06 10.1038/nrgastro.2009.177 http://dx.doi.org/10.1038/nrgastro.2009.177 Review http://dx.doi.org/10.1038/nrgastro.2009.177