Nature Reviews Immunology
Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defence mechanisms, how the body defends itself against disease, and what happens when it all goes wrong. Nature Reviews Immunology provides in-depth coverage of this field, from fundamental mechanisms to translational aspects of basic research, and reviews the field’s most important developments. All Review and Perspective articles are carefully commissioned by the editors and written by leaders in the field. Articles are subject to rigorous peer review and provide high-quality and authoritative coverage of the field in each issue. Articles are carefully tailored by the editors to provide accessible information for non-specialists, and this is additionally enhanced with the use of Glossary terms and highlighted references. Each issue also contains Research Highlight articles – short pieces written by the editors that summarize the results from recent hot research papers.
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Nature Reviews Immunology
© 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
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Nature Reviews Immunology
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https://www.nature.com/articles/s41577-024-01003-x
Nature Reviews Immunology, Published online: 15 March 2024; doi:10.1038/s41577-024-01003-xHaematological malignancies are associated with inflammation in the bone marrow. In this Review, the authors discuss how tumour-associated inflammation affects the normal functions of the bone marrow and supports the outgrowth and survival of malignant cells. Moreover, they describe how the inflammatory changes in the bone marrow differ in myeloid and lymphoid malignancies.]]>
Madelon M. E. de JongLanpeng ChenMarc H. G. P. RaaijmakersTom Cupedo
doi:10.1038/s41577-024-01003-x
Nature Reviews Immunology, Published online: 2024-03-15; | doi:10.1038/s41577-024-01003-x
2024-03-15
Nature Reviews Immunology
10.1038/s41577-024-01003-x
https://www.nature.com/articles/s41577-024-01003-x
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https://www.nature.com/articles/s41577-024-01008-6
Nature Reviews Immunology, Published online: 14 March 2024; doi:10.1038/s41577-024-01008-6This Review explains how cytokines contribute to the pathogenesis of inflammatory bowel disease (IBD). The author highlights the cytokine-targeting drugs that are already being successfully used in the clinic and discusses the potential of other cytokine-modulating drugs in IBD.]]>
Markus F. Neurath
doi:10.1038/s41577-024-01008-6
Nature Reviews Immunology, Published online: 2024-03-14; | doi:10.1038/s41577-024-01008-6
2024-03-14
Nature Reviews Immunology
10.1038/s41577-024-01008-6
https://www.nature.com/articles/s41577-024-01008-6
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https://www.nature.com/articles/s41577-024-01023-7
Nature Reviews Immunology, Published online: 13 March 2024; doi:10.1038/s41577-024-01023-7Author Correction: Using BCG vaccination to protect against COVID-19: when reality fails to meet expectation]]>
Laure F. PittetChristie C. A. NobleNicole L. MessinaNigel Curtis
doi:10.1038/s41577-024-01023-7
Nature Reviews Immunology, Published online: 2024-03-13; | doi:10.1038/s41577-024-01023-7
2024-03-13
Nature Reviews Immunology
10.1038/s41577-024-01023-7
https://www.nature.com/articles/s41577-024-01023-7
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https://www.nature.com/articles/s41577-024-01010-y
Nature Reviews Immunology, Published online: 12 March 2024; doi:10.1038/s41577-024-01010-yIn this Perspective article, Ley and colleagues explain the association between atherosclerosis and the loss of tolerance to self-proteins. They discuss why re-establishing immune tolerance could improve outcomes for patients with atherosclerotic cardiovascular disease.]]>
Amir KhanPayel RoyKlaus Ley
doi:10.1038/s41577-024-01010-y
Nature Reviews Immunology, Published online: 2024-03-12; | doi:10.1038/s41577-024-01010-y
2024-03-12
Nature Reviews Immunology
10.1038/s41577-024-01010-y
https://www.nature.com/articles/s41577-024-01010-y
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+ T cells]]>
https://www.nature.com/articles/s41577-024-01020-w
Nature Reviews Immunology, Published online: 11 March 2024; doi:10.1038/s41577-024-01020-wRegulation of innate-like activities of neonatal CD8+ T cells]]>
+ T cells]]>
Alexandra Flemming
doi:10.1038/s41577-024-01020-w
Nature Reviews Immunology, Published online: 2024-03-11; | doi:10.1038/s41577-024-01020-w
2024-03-11
Nature Reviews Immunology
10.1038/s41577-024-01020-w
https://www.nature.com/articles/s41577-024-01020-w
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https://www.nature.com/articles/s41577-024-01019-3
Nature Reviews Immunology, Published online: 11 March 2024; doi:10.1038/s41577-024-01019-3The eye provides an immunological gateway to the brain]]>
Alexandra Flemming
doi:10.1038/s41577-024-01019-3
Nature Reviews Immunology, Published online: 2024-03-11; | doi:10.1038/s41577-024-01019-3
2024-03-11
Nature Reviews Immunology
10.1038/s41577-024-01019-3
https://www.nature.com/articles/s41577-024-01019-3
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+ T cells in response to HIV entry]]>
https://www.nature.com/articles/s41577-024-01021-9
Nature Reviews Immunology, Published online: 11 March 2024; doi:10.1038/s41577-024-01021-9CARD8 kills CD4+ T cells in response to HIV entry]]>
+ T cells in response to HIV entry]]>
Alexandra Flemming
doi:10.1038/s41577-024-01021-9
Nature Reviews Immunology, Published online: 2024-03-11; | doi:10.1038/s41577-024-01021-9
2024-03-11
Nature Reviews Immunology
10.1038/s41577-024-01021-9
https://www.nature.com/articles/s41577-024-01021-9
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https://www.nature.com/articles/s41577-024-00998-7
Nature Reviews Immunology, Published online: 11 March 2024; doi:10.1038/s41577-024-00998-7Acute infection and other insults cause extensive remodelling in the bone marrow to drive the production of new blood cells, often prioritizing the production of mature myeloid cells at the expense of other blood cell types. Here, the authors describe how haematopoiesis is affected by acute demand and how this can contribute to inflammatory disease and cancer when dysregulated.]]>
James W. SwannOakley C. OlsonEmmanuelle Passegué
doi:10.1038/s41577-024-00998-7
Nature Reviews Immunology, Published online: 2024-03-11; | doi:10.1038/s41577-024-00998-7
2024-03-11
Nature Reviews Immunology
10.1038/s41577-024-00998-7
https://www.nature.com/articles/s41577-024-00998-7