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Volume 13 Issue 5, May 2006

The satellite dish array receives and transmits signals into the cosmos above. New data from Park et al. suggest that the bacterial chemotaxis proteins responsible for sensing and signaling in response to environmental stimuli are arranged in a similar hedgerow-like array in the cell. pp 400-407 pp 382

Volume 13 Issue 5

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  • New biochemical experiments with the retroelement restriction protein APOBEC3G indicate that it processively deaminates single-stranded DNA cytosines by a unique jumping and sliding mechanism.

    • Reuben S Harris
    • Hiroshi Matsuo
    News & Views

  • Bacterial chemotaxis systems have cooperatively interacting clusters of transmembrane receptors and signaling proteins to detect, amplify, integrate and adapt to environmental signals. A recent study provides experimental data to construct a new model of the signaling complex.

    • Robert M Weis
    News & Views

  • A major challenge in gene expression is to understand how precursor messenger RNA (pre-mRNA) processing events are integrated with transcription. A recent study suggests that distant exons in nascent RNA are held together during transcription, promoting accurate splicing independent of intron fate.

    • Karla M Neugebauer
    News & Views

  • Protein complexes at telomeres have been assumed to present an obstacle to the passing replication fork. The observation that the Schizosaccharomyces pombe telomere-binding protein Taz1 is required for replication suggests otherwise.

    • Jan Karlseder
    News & Views

  • Two new studies demonstrate that transmembrane voltage-sensing domains can act without an obvious pore-forming domain to sense membrane potential changes and make a proton-selective pore.

    • Daniel L Minor Jr
    News & Views
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