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Thyroid hormone receptor mutants implicated in human hepatocellular carcinoma display an altered target gene repertoire

I H Chan — 2009-07-14

Thyroid hormone receptor mutants implicated in human hepatocellular carcinoma display an altered target gene repertoire

Oncogene advance online publication, September 14, 2009. doi:10.1038/onc.2009.265

Authors: I H Chan & M L Privalsky

LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer

D C T Ong — 2009-07-07

LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer

Oncogene advance online publication, September 7, 2009. doi:10.1038/onc.2009.266

Authors: D C T Ong, Y M Ho, C Rudduck, K Chin, W -L Kuo, D K H Lie, C L M Chua, P H Tan, K W Eu, F Seow-Choen, C Y Wong, G S Hong, J W Gray & A S G Lee

Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation

F V Jacinto — 2009-07-07

Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation

Oncogene advance online publication, September 7, 2009. doi:10.1038/onc.2009.267

Authors: F V Jacinto, E Ballestar & M Esteller

Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene

M Jaskelioff — 2009-07-07

Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene

Oncogene advance online publication, September 7, 2009. doi:10.1038/onc.2009.268

Authors: M Jaskelioff, W Song, J Xia, C Liu, J Kramer, S Koido, S J Gendler, S K Calderwood & J Gong

The Cdk inhibitor p57Kip2 controls LIM-kinase 1 activity and regulates actin cytoskeleton dynamics

P Vlachos — 2009-07-07

The Cdk inhibitor p57Kip2 controls LIM-kinase 1 activity and regulates actin cytoskeleton dynamics

Oncogene advance online publication, September 7, 2009. doi:10.1038/onc.2009.269

Authors: P Vlachos & B Joseph

Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation

Y Aylon — 2009-10-26

Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation

Oncogene advance online publication, October 26, 2009. doi:10.1038/onc.2009.270

Authors: Y Aylon, N Yabuta, H Besserglick, Y Buganim, V Rotter, H Nojima & M Oren

A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer

R Najdi — 2009-07-14

A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer

Oncogene advance online publication, September 14, 2009. doi:10.1038/onc.2009.271

Authors: R Najdi, A Syed, L Arce, H Theisen, J-HT Ting, F Atcha, A V Nguyen, M Martinez, R F Holcombe, R A Edwards, J L Marsh & M L Waterman

A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis

J S Blackburn — 2009-07-07

A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis

Oncogene advance online publication, September 7, 2009. doi:10.1038/onc.2009.272

Authors: J S Blackburn, I Liu, C I Coon & C E Brinckerhoff

RNA aptamers interfering with nucleophosmin oligomerization induce apoptosis of cancer cells

Y Jian — 2009-07-07

RNA aptamers interfering with nucleophosmin oligomerization induce apoptosis of cancer cells

Oncogene advance online publication, September 7, 2009. doi:10.1038/onc.2009.275

Authors: Y Jian, Z Gao, J Sun, Q Shen, F Feng, Y Jing & C Yang

PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis

J J Gu — 2009-07-14

PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis

Oncogene advance online publication, September 14, 2009. doi:10.1038/onc.2009.276

Authors: J J Gu, Z Wang, R Reeves & N S Magnuson

Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines

K A Olaussen — 2009-07-14

Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines

Oncogene advance online publication, September 14, 2009. doi:10.1038/onc.2009.277

Authors: K A Olaussen, F Commo, M Tailler, L Lacroix, I Vitale, S Q Raza, C Richon, P Dessen, V Lazar, J -C Soria & G Kroemer

Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration

X Li — 2009-07-21

Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration

Oncogene advance online publication, September 21, 2009. doi:10.1038/onc.2009.278

Authors: X Li, Y Shen, H Ichikawa, T Antes & G S Goldberg

Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type- and mutation-specific manner

E di Martino — 2009-07-14

Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type- and mutation-specific manner

Oncogene advance online publication, September 14, 2009. doi:10.1038/onc.2009.280

Authors: E di Martino, C G L'Hôte, W Kennedy, D C Tomlinson & M A Knowles

Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions

D Walerych — 2009-07-14

Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions

Oncogene advance online publication, September 14, 2009. doi:10.1038/onc.2009.281

Authors: D Walerych, M B Olszewski, M Gutkowska, A Helwak, M Zylicz & A Zylicz

Pro-proliferative FoxM1 is a target of p53-mediated repression

A M Barsotti — 2009-07-14

Pro-proliferative FoxM1 is a target of p53-mediated repression

Oncogene advance online publication, September 14, 2009. doi:10.1038/onc.2009.282

Authors: A M Barsotti & C Prives

Pannexin2 as a novel growth regulator in C6 glioma cells

C P K Lai — 2009-07-14

Pannexin2 as a novel growth regulator in C6 glioma cells

Oncogene advance online publication, September 14, 2009. doi:10.1038/onc.2009.283

Authors: C P K Lai, J F Bechberger & C C Naus

‘Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma’

J L Orgaz — 2009-07-21

‘Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma’

Oncogene advance online publication, September 21, 2009. doi:10.1038/onc.2009.284

Authors: J L Orgaz, O Ladhani, K S Hoek, A Fernández-Barral, D Mihic, O Aguilera, E A Seftor, A Bernad, J L Rodríguez-Peralto, M J C Hendrix, O V Volpert & B Jiménez

SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue

C Peña — 2009-10-05

SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.285

Authors: C Peña, J M García, M J Larriba, R Barderas, I Gómez, M Herrera, V García, J Silva, G Domínguez, R Rodríguez, J Cuevas, A G de Herreros, J I Casal, A Muñoz & F Bonilla

Genetic inactivation of ApoJ/clusterin: effects on prostate tumourigenesis and metastatic spread

S Bettuzzi — 2009-07-28

Genetic inactivation of ApoJ/clusterin: effects on prostate tumourigenesis and metastatic spread

Oncogene advance online publication, September 28, 2009. doi:10.1038/onc.2009.286

Authors: S Bettuzzi, P Davalli, S Davoli, O Chayka, F Rizzi, L Belloni, D Pellacani, G Fregni, S Astancolle, M Fassan, A Corti, R Baffa & A Sala

Lysine 269 is essential for cyclin D1 ubiquitylation by the SCFFbx4/αB-crystallin ligase and subsequent proteasome-dependent degradation

O Barbash — 2009-07-21

Lysine 269 is essential for cyclin D1 ubiquitylation by the SCFFbx4/αB-crystallin ligase and subsequent proteasome-dependent degradation

Oncogene advance online publication, September 21, 2009. doi:10.1038/onc.2009.287

Authors: O Barbash, E Egan, L L Pontano, J Kosak & J A Diehl

Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells

M Shimabe — 2009-07-21

Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells

Oncogene advance online publication, September 21, 2009. doi:10.1038/onc.2009.288

Authors: M Shimabe, S Goyama, N Watanabe-Okochi, A Yoshimi, M Ichikawa, Y Imai & M Kurokawa

TLR4 signaling induced by lipopolysaccharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer

M Szajnik — 2009-10-12

TLR4 signaling induced by lipopolysaccharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer

Oncogene advance online publication, October 12, 2009. doi:10.1038/onc.2009.289

Authors: M Szajnik, M J Szczepanski, M Czystowska, E Elishaev, M Mandapathil, E Nowak-Markwitz, M Spaczynski & T L Whiteside

Transcription activity is required for p53-dependent tumor suppression

O Gaidarenko — 2009-07-21

Transcription activity is required for p53-dependent tumor suppression

Oncogene advance online publication, September 21, 2009. doi:10.1038/onc.2009.290

Authors: O Gaidarenko & Y Xu

Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells

S Hassan — 2009-07-21

Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells

Oncogene advance online publication, September 21, 2009. doi:10.1038/onc.2009.291

Authors: S Hassan, M H U Biswas, C Zhang, C Du & K C Balaji

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis

R Shao — 2009-07-21

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis

Oncogene advance online publication, September 21, 2009. doi:10.1038/onc.2009.292

Authors: R Shao, K Hamel, L Petersen, Q J Cao, R B Arenas, C Bigelow, B Bentley & W Yan

A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways

V Mamidipudi — 2009-07-21

A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways

Oncogene advance online publication, September 21, 2009. doi:10.1038/onc.2009.293

Authors: V Mamidipudi & C A Cartwright

The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts

A Shaw — 2009-07-28

The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts

Oncogene advance online publication, September 28, 2009. doi:10.1038/onc.2009.294

Authors: A Shaw, J Gipp & W Bushman

Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer

J Mullenders — 2009-07-21

Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer

Oncogene advance online publication, September 21, 2009. doi:10.1038/onc.2009.295

Authors: J Mullenders & R Bernards

The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer

A Mira — 2009-10-19

The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.296

Authors: A Mira, C Isella, T Renzulli, D Cantarella, M L Martelli & E Medico

Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

G Liu — 2009-07-28

Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

Oncogene advance online publication, September 28, 2009. doi:10.1038/onc.2009.297

Authors: G Liu, A Bollig-Fischer, B Kreike, M J van de Vijver, J Abrams, S P Ethier & Z -Q Yang

PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression

Y Lee — 2009-07-28

PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression

Oncogene advance online publication, September 28, 2009. doi:10.1038/onc.2009.298

Authors: Y Lee, S J Kim, H D Park, E H Park, S M Huang, S B Jeon, J-M Kim, D-S Lim & S S Koh

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

P P Provenzano — 2009-10-12

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

Oncogene advance online publication, October 12, 2009. doi:10.1038/onc.2009.299

Authors: P P Provenzano, D R Inman, K W Eliceiri & P J Keely

Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein

M R Abedini — 2009-10-05

Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.300

Authors: M R Abedini, E J Muller, R Bergeron, D A Gray & B K Tsang

Functional variant of KLOTHO: a breast cancer risk modifier among BRCA1 mutation carriers of Ashkenazi origin

I Wolf — 2009-10-05

Functional variant of KLOTHO: a breast cancer risk modifier among BRCA1 mutation carriers of Ashkenazi origin

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.301

Authors: I Wolf, Y Laitman, T Rubinek, L Abramovitz, I Novikov, R Beeri, M Kuro-O, H P Koeffler, R Catane, L S Freedman, E Levy-Lahad, B Y Karlan, E Friedman & B Kaufman

Downregulation of E-cadherin is an essential event in activating β-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells

Q Wang — 2009-07-28

Downregulation of E-cadherin is an essential event in activating β-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells

Oncogene advance online publication, September 28, 2009. doi:10.1038/onc.2009.302

Authors: Q Wang, Z -X Sun, H Allgayer & H -S Yang

RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1

C A Reed — 2009-10-19

RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.303

Authors: C A Reed, C N Mayhew, A K McClendon, X Yang, A Witkiewicz & E S Knudsen

Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma

B Keenen — 2009-07-28

Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma

Oncogene advance online publication, September 28, 2009. doi:10.1038/onc.2009.304

Authors: B Keenen, H Qi, S V Saladi, M Yeung & I L de la Serna

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

M P O’Connell — 2009-10-05

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.305

Authors: M P O’Connell, J L Fiori, M Xu, A D Carter, B P Frank, T C Camilli, A D French, S K Dissanayake, F E Indig, M Bernier, D D Taub, S M Hewitt & A T Weeraratna

Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation

E Borbone — 2009-10-05

Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.306

Authors: E Borbone, M T Berlingieri, F De Bellis, A Nebbioso, G Chiappetta, A Mai, L Altucci & A Fusco

RalA suppresses early stages of Ras-induced squamous cell carcinoma progression

A G Sowalsky — 2009-10-05

RalA suppresses early stages of Ras-induced squamous cell carcinoma progression

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.307

Authors: A G Sowalsky, A Alt-Holland, Y Shamis, J A Garlick & L A Feig

HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions

M A Villaronga — 2009-10-05

HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.309

Authors: M A Villaronga, D N Lavery, C L Bevan, S Llanos & B Belandia

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways

R van Amerongen — 2009-10-05

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.310

Authors: R van Amerongen, M C Nawijn, J -P Lambooij, N Proost, J Jonkers & A Berns

Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells

P Nirdé — 2009-10-05

Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.311

Authors: P Nirdé, D Derocq, M Maynadier, M Chambon, I Basile, M Gary-Bobo & M Garcia

Shc is required for ErbB2-induced inhibition of apoptosis but is dispensable for cell proliferation and disruption of cell polarity

A V Lucs — 2009-10-12

Shc is required for ErbB2-induced inhibition of apoptosis but is dispensable for cell proliferation and disruption of cell polarity

Oncogene advance online publication, October 12, 2009. doi:10.1038/onc.2009.312

Authors: A V Lucs, W J Muller & S K Muthuswamy

Modeling the effect of the RB tumor suppressor on disease progression: dependence on oncogene network and cellular context

J L Dean — 2009-10-05

Modeling the effect of the RB tumor suppressor on disease progression: dependence on oncogene network and cellular context

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.313

Authors: J L Dean, A K McClendon, K R Stengel & E S Knudsen

Chemotherapy induces NEDP1-mediated destabilization of MDM2

I R Watson — 2009-07-28

Chemotherapy induces NEDP1-mediated destabilization of MDM2

Oncogene advance online publication, September 28, 2009. doi:10.1038/onc.2009.314

Authors: I R Watson, B K Li, O Roche, A Blanch, M Ohh & M S Irwin

AKT1 mutations in bladder cancer: identification of a novel oncogenic mutation that can co-operate with E17K

J M Askham — 2009-10-05

AKT1 mutations in bladder cancer: identification of a novel oncogenic mutation that can co-operate with E17K

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.315

Authors: J M Askham, F Platt, P A Chambers, H Snowden, C F Taylor & M A Knowles

The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival

D Sachdev — 2009-10-19

The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.316

Authors: D Sachdev, X Zhang, I Matise, M Gaillard-Kelly & D Yee

Selective inhibition of choline kinase simultaneously attenuates MAPK and PI3K/AKT signaling

A Yalcin — 2009-10-26

Selective inhibition of choline kinase simultaneously attenuates MAPK and PI3K/AKT signaling

Oncogene advance online publication, October 26, 2009. doi:10.1038/onc.2009.317

Authors: A Yalcin, B Clem, S Makoni, A Clem, K Nelson, J Thornburg, D Siow, A N Lane, S E Brock, U Goswami, J W Eaton, S Telang & J Chesney

Cytokine expression and signaling in drug-induced cellular senescence

Z Novakova — 2009-10-05

Cytokine expression and signaling in drug-induced cellular senescence

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.318

Authors: Z Novakova, S Hubackova, M Kosar, L Janderova-Rossmeislova, J Dobrovolna, P Vasicova, M Vancurova, Z Horejsi, P Hozak, J Bartek & Z Hodny

Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin–proteasome pathway

Y Yoo — 2009-10-05

Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin–proteasome pathway

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.319

Authors: Y Yoo, H J Ho, C Wang & J -L Guan

c-Kit mutants require hypoxia-inducible factor 1α to transform melanocytes

G Monsel — 2009-10-05

c-Kit mutants require hypoxia-inducible factor 1α to transform melanocytes

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.320

Authors: G Monsel, N Ortonne, M Bagot, A Bensussan & N Dumaz

Genotoxic stress-induced nuclear localization of oncoprotein YB-1 in the absence of proteolytic processing

S B Cohen — 2009-10-19

Genotoxic stress-induced nuclear localization of oncoprotein YB-1 in the absence of proteolytic processing

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.321

Authors: S B Cohen, W Ma, V A Valova, M Algie, R Harfoot, A G Woolley, P J Robinson & A W Braithwaite

Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression

M Shiota — 2009-10-05

Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression

Oncogene advance online publication, October 5, 2009. doi:10.1038/onc.2009.322

Authors: M Shiota, A Yokomizo, Y Tada, J Inokuchi, E Kashiwagi, D Masubuchi, M Eto, T Uchiumi & S Naito

Notch-1 activates estrogen receptor-α-dependent transcription via IKKα in breast cancer cells

L Hao — 2009-10-19

Notch-1 activates estrogen receptor-α-dependent transcription via IKKα in breast cancer cells

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.323

Authors: L Hao, P Rizzo, C Osipo, A Pannuti, D Wyatt, L W-K Cheung, G Sonenshein, B A Osborne & L Miele

HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability

M Krishnan — 200-11-02

HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.324

Authors: M Krishnan, A B Singh, J J Smith, A Sharma, X Chen, S Eschrich, T J Yeatman, R D Beauchamp & P Dhawan

The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression

R Wäsch — 2009-10-12

The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression

Oncogene advance online publication, October 12, 2009. doi:10.1038/onc.2009.325

Authors: R Wäsch, J A Robbins & F R Cross

Tumor suppressor U19/EAF2 regulates thrombospondin-1 expression via p53

F Su — 2009-10-12

Tumor suppressor U19/EAF2 regulates thrombospondin-1 expression via p53

Oncogene advance online publication, October 12, 2009. doi:10.1038/onc.2009.326

Authors: F Su, L E Pascal, W Xiao & Z Wang

Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy

J Yang — 2009-10-19

Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.327

Authors: J Yang, J Parsons, N H Nicolay, S Caporali, C F Harrington, R Singh, D Finch, S D’Atri, P B Farmer, P G Johnston, W G McKenna, G Dianov & R A Sharma

Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis

C Puri — 2009-10-26

Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis

Oncogene advance online publication, October 26, 2009. doi:10.1038/onc.2009.328

Authors: C Puri, M V Chibalina, S D Arden, A J Kruppa, J Kendrick-Jones & F Buss

Knockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machinery

F J Rodríguez-Ubreva — 2009-10-19

Knockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machinery

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.329

Authors: F J Rodríguez-Ubreva, A E Cariaga-Martinez, M A Cortés, M Romero-De Pablos, S Ropero, P López-Ruiz & B Colás

MdmX is a substrate for the deubiquitinating enzyme USP2a

N Allende-Vega — 2009-10-19

MdmX is a substrate for the deubiquitinating enzyme USP2a

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.330

Authors: N Allende-Vega, A Sparks, D P Lane & M K Saville

The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells

M N Thobe — 2009-10-19

The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.331

Authors: M N Thobe, D Gurusamy, P Pathrose & S E Waltz

Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis

X Liu — 200-11-02

Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.332

Authors: X Liu, X Wang, J Zhang, E K Y Lam, V Y Shin, A S L Cheng, J Yu, F K L Chan, J J Y Sung & H C Jin

Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation

J P Robinson — 2009-10-26

Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation

Oncogene advance online publication, October 26, 2009. doi:10.1038/onc.2009.333

Authors: J P Robinson, M W VanBrocklin, A R Guilbeault, D L Signorelli, S Brandner & S L Holmen

Histone deacetylases and the immunological network: implications in cancer and inflammation

A Villagra — 2009-10-26

Histone deacetylases and the immunological network: implications in cancer and inflammation

Oncogene advance online publication, October 26, 2009. doi:10.1038/onc.2009.334

Authors: A Villagra, E M Sotomayor & E Seto

Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway

N H Thoennissen — 2009-10-26

Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway

Oncogene advance online publication, October 26, 2009. doi:10.1038/onc.2009.335

Authors: N H Thoennissen, J O'Kelly, D Lu, G B Iwanski, D T La, S Abbassi, A Leiter, B Karlan, R Mehta & H P Koeffler

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling

A B Hanker — 2009-10-19

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.336

Authors: A B Hanker, N Mitin, R S Wilder, E P Henske, F Tamanoi, A D Cox & C J Der

Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth

S Chandarlapaty — 2009-10-26

Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth

Oncogene advance online publication, October 26, 2009. doi:10.1038/onc.2009.337

Authors: S Chandarlapaty, M Scaltriti, P Angelini, Q Ye, M Guzman, C A Hudis, L Norton, D B Solit, J Arribas, J Baselga & N Rosen

Extracellular cleavage and shedding of P-cadherin: a mechanism underlying the invasive behaviour of breast cancer cells

A S Ribeiro — 200-11-09

Extracellular cleavage and shedding of P-cadherin: a mechanism underlying the invasive behaviour of breast cancer cells

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.338

Authors: A S Ribeiro, A Albergaria, B Sousa, A L Correia, M Bracke, R Seruca, F C Schmitt & J Paredes

Wnt signaling activation and mammary gland hyperplasia in MMTV–LRP6 transgenic mice: implication for breast cancer tumorigenesis

J Zhang — 200-11-02

Wnt signaling activation and mammary gland hyperplasia in MMTV–LRP6 transgenic mice: implication for breast cancer tumorigenesis

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.339

Authors: J Zhang, Y Li, Q Liu, W Lu & G Bu

DNA damage induces Chk1-dependent threonine-160 phosphorylation and activation of Cdk2

E Bourke — 2009-10-19

DNA damage induces Chk1-dependent threonine-160 phosphorylation and activation of Cdk2

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.340

Authors: E Bourke, J A L Brown, S Takeda, H Hochegger & C G Morrison

Serum protein signature may improve detection of ductal carcinoma in situ of the breast

J Solassol — 2009-10-26

Serum protein signature may improve detection of ductal carcinoma in situ of the breast

Oncogene advance online publication, October 26, 2009. doi:10.1038/onc.2009.341

Authors: J Solassol, P Rouanet, P J Lamy, C Allal, G Favre, T Maudelonde & A Mangé

Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-κB activity in hypoxic tumor cells

G -Y Jang — 2009-10-19

Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-κB activity in hypoxic tumor cells

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.342

Authors: G -Y Jang, J -H Jeon, S -Y Cho, D -M Shin, C -W Kim, E M Jeong, H C Bae, T W Kim, S -H Lee, Y Choi, D -S Lee, S -C Park & I -G Kim

Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells

K Zhu — 200-11-02

Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.343

Authors: K Zhu, K Dunner & D J McConkey

Roles of PKC isoforms in the induction of apoptosis elicited by aberrant Ras

T Zhu — 2009-10-19

Roles of PKC isoforms in the induction of apoptosis elicited by aberrant Ras

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.344

Authors: T Zhu, T Tsuji & C Chen

The Rap GTPases regulate the migration, invasiveness and in vivo dissemination of B-cell lymphomas

K B L Lin — 2009-10-19

The Rap GTPases regulate the migration, invasiveness and in vivo dissemination of B-cell lymphomas

Oncogene advance online publication, October 19, 2009. doi:10.1038/onc.2009.345

Authors: K B L Lin, P Tan, S A Freeman, M Lam, K M McNagny & M R Gold

Prevention of premature senescence requires JNK regulation of Bcl-2 and reactive oxygen species

J -J Lee — 2009-10-26

Prevention of premature senescence requires JNK regulation of Bcl-2 and reactive oxygen species

Oncogene advance online publication, October 26, 2009. doi:10.1038/onc.2009.355

Authors: J -J Lee, J -H Lee, Y -G Ko, S I Hong & J -S Lee

Immunogenic death of colon cancer cells treated with oxaliplatin

A Tesniere — 200-11-02

Immunogenic death of colon cancer cells treated with oxaliplatin

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.356

Authors: A Tesniere, F Schlemmer, V Boige, O Kepp, I Martins, F Ghiringhelli, L Aymeric, M Michaud, L Apetoh, L Barault, J Mendiboure, J-P Pignon, V Jooste, P van Endert, M Ducreux, L Zitvogel, F Piard & G Kroemer

UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratinocytes

M Ming — 200-11-02

UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratinocytes

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.357

Authors: M Ming, W Han, J Maddox, K Soltani, C R Shea, D M Freeman & Y -Y He

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

R J DeBerardinis — 200-11-02

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.358

Authors: R J DeBerardinis & T Cheng

Chromosomal rearrangements after ex vivo Epstein–Barr virus (EBV) infection of human B cells

S Lacoste — 200-11-02

Chromosomal rearrangements after ex vivo Epstein–Barr virus (EBV) infection of human B cells

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.359

Authors: S Lacoste, E Wiechec, A G dos Santos Silva, A Guffei, G Williams, M Lowbeer, K Benedek, M Henriksson, G Klein & S Mai

Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis

S J Miller — 200-11-09

Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.360

Authors: S J Miller, Z D Lan, A Hardiman, J Wu, J J Kordich, D M Patmore, R S Hegde, T P Cripe, J A Cancelas, M H Collins & N Ratner

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition

A Lakshmikuttyamma — 200-11-02

Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.361

Authors: A Lakshmikuttyamma, S A Scott, J F DeCoteau & C R Geyer

BAG-1 overexpression attenuates luminal apoptosis in MCF-10A mammary epithelial cells through enhanced RAF-1 activation

L R Anderson — 200-11-02

BAG-1 overexpression attenuates luminal apoptosis in MCF-10A mammary epithelial cells through enhanced RAF-1 activation

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.362

Authors: L R Anderson, R L Sutherland & A J Butt

Differential phosphorylation of the docking protein Gab1 by c-Src and the hepatocyte growth factor receptor regulates different aspects of cell functions

P-C Chan — 200-11-02

Differential phosphorylation of the docking protein Gab1 by c-Src and the hepatocyte growth factor receptor regulates different aspects of cell functions

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.363

Authors: P-C Chan, J N Sudhakar, C-C Lai & H-C Chen

Focal amplification and oncogene dependency of GAB2 in breast cancer

M Bocanegra — 200-11-02

Focal amplification and oncogene dependency of GAB2 in breast cancer

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.364

Authors: M Bocanegra, A Bergamaschi, Y H Kim, M A Miller, A B Rajput, J Kao, A Langerød, W Han, D -Y Noh, S S Jeffrey, D G Huntsman, A -L Børresen-Dale & J R Pollack

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis

H Lemjabbar-Alaoui — 2009-10-26

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis

Oncogene advance online publication, October 26, 2009. doi:10.1038/onc.2009.365

Authors: H Lemjabbar-Alaoui, A van Zante, M S Singer, Q Xue, Y -Q Wang, D Tsay, B He, D M Jablons & S D Rosen

Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim

J Konishi — 200-11-02

Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.366

Authors: J Konishi, F Yi, X Chen, H Vo, D P Carbone & T P Dang

LIM-kinase 2, a regulator of actin dynamics, is involved in mitotic spindle integrity and sensitivity to microtubule-destabilizing drugs

S T Po'uha — 200-11-02

LIM-kinase 2, a regulator of actin dynamics, is involved in mitotic spindle integrity and sensitivity to microtubule-destabilizing drugs

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.367

Authors: S T Po'uha, M S Y Shum, A Goebel, O Bernard & M Kavallaris

Enhanced mRNA cap methylation increases Cyclin D1 expression and promotes cell transformation

V H Cowling — 200-11-16

Enhanced mRNA cap methylation increases Cyclin D1 expression and promotes cell transformation

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.368

Author: V H Cowling

Characterization of a major colon cancer susceptibility locus (Ccs3) on mouse chromosome 3

C Meunier — 200-11-16

Characterization of a major colon cancer susceptibility locus (Ccs3) on mouse chromosome 3

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.369

Authors: C Meunier, J Cai, A Fortin, T Kwan, J -F Marquis, C Turbide, L Van Der Kraak, S Jothy, N Beauchemin & P Gros

Knockdown of peroxisome proliferator-activated receptor-β induces less differentiation and enhances cell–fibronectin adhesion of colon cancer cells

L Yang — 200-11-23

Knockdown of peroxisome proliferator-activated receptor-β induces less differentiation and enhances cell–fibronectin adhesion of colon cancer cells

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.370

Authors: L Yang, B Olsson, D Pfeifer, J -I Jönsson, Z -G Zhou, X Jiang, B -A Fredriksson, H Zhang & X -F Sun

ARF antagonizes the ability of Miz-1 to inhibit p53-mediated transactivation

L Miao — 200-11-09

ARF antagonizes the ability of Miz-1 to inhibit p53-mediated transactivation

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.372

Authors: L Miao, Z Song, L Jin, Y M Zhu, L P Wen & M Wu

C/EBPα redirects androgen receptor signaling through a unique bimodal interaction

J Zhang — 200-11-09

C/EBPα redirects androgen receptor signaling through a unique bimodal interaction

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.373

Authors: J Zhang, M Gonit, M D Salazar, A Shatnawi, L Shemshedini, R Trumbly & M Ratnam

Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-γ1-driven activation of mTOR/p70S6-kinase pathway

B Markova — 200-11-02

Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-γ1-driven activation of mTOR/p70S6-kinase pathway

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.374

Authors: B Markova, C Albers, F Breitenbuecher, J V Melo, T H Brümmendorf, F Heidel, D Lipka, J Duyster, C Huber & T Fischer

Synergistic action of Smad4 and Pten in suppressing pancreatic ductal adenocarcinoma formation in mice

X Xu — 200-11-09

Synergistic action of Smad4 and Pten in suppressing pancreatic ductal adenocarcinoma formation in mice

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.375

Authors: X Xu, B Ehdaie, N Ohara, T Yoshino & C -X Deng

A common gain of function of p53 cancer mutants in inducing genetic instability

D P Liu — 200-11-02

A common gain of function of p53 cancer mutants in inducing genetic instability

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.376

Authors: D P Liu, H Song & Y Xu

c-Myc overexpression promotes a germinal center-like program in Burkitt's lymphoma

H Scheller — 200-11-02

c-Myc overexpression promotes a germinal center-like program in Burkitt's lymphoma

Oncogene advance online publication, November 2, 2009. doi:10.1038/onc.2009.377

Authors: H Scheller, S Tobollik, A Kutzera, M Eder, J Unterlehberg, I Pfeil & B Jungnickel

A ‘DNA replication’ signature of progression and negative outcome in colorectal cancer

M-J Pillaire — 200-11-09

A ‘DNA replication’ signature of progression and negative outcome in colorectal cancer

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.378

Authors: M-J Pillaire, J Selves, K Gordien, P-A Gouraud, C Gentil, M Danjoux, C Do, V Negre, A Bieth, R Guimbaud, D Trouche, P Pasero, M Méchali, J-S Hoffmann & C Cazaux

Interferon-induced transmembrane 3 binds osteopontin in vitro: expressed in vivo IFITM3 reduced OPN expression

M K El-Tanani — 200-11-09

Interferon-induced transmembrane 3 binds osteopontin in vitro: expressed in vivo IFITM3 reduced OPN expression

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.379

Authors: M K El-Tanani, D Jin, F C Campbell & P G Johnston

Roles of the translationally controlled tumour protein (TCTP) and the double-stranded RNA-dependent protein kinase, PKR, in cellular stress responses

U-A Bommer — 200-11-09

Roles of the translationally controlled tumour protein (TCTP) and the double-stranded RNA-dependent protein kinase, PKR, in cellular stress responses

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.380

Authors: U-A Bommer, C Heng, A Perrin, P Dash, S Lobov, A Elia & M J Clemens

Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling

A H Beck — 200-11-09

Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.381

Authors: A H Beck, C-H Lee, D M Witten, B C Gleason, B Edris, I Espinosa, S Zhu, R Li, K D Montgomery, R J Marinelli, R Tibshirani, T Hastie, D M Jablons, B P Rubin, C D Fletcher, R B West & M van de Rijn

Dual engagement of 14-3-3 proteins controls signal relay from ASK2 to the ASK1 signalosome

L M Cockrell — 200-11-23

Dual engagement of 14-3-3 proteins controls signal relay from ASK2 to the ASK1 signalosome

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.382

Authors: L M Cockrell, M C Puckett, E H Goldman, F R Khuri & H Fu

Anthrax toxin receptor 2 is expressed in murine and tumor vasculature and functions in endothelial proliferation and morphogenesis

C V Reeves — 200-11-09

Anthrax toxin receptor 2 is expressed in murine and tumor vasculature and functions in endothelial proliferation and morphogenesis

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.383

Authors: C V Reeves, J Dufraine, J A T Young & J Kitajewski

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN

L Davidson — 200-11-16

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.384

Authors: L Davidson, H Maccario, N M Perera, X Yang, L Spinelli, P Tibarewal, B Glancy, A Gray, C J Weijer, C P Downes & N R Leslie

Activity and cellular localization of an oncogenic glioblastoma multiforme-associated EGF receptor mutant possessing a duplicated kinase domain

B H Ozer — 200-11-16

Activity and cellular localization of an oncogenic glioblastoma multiforme-associated EGF receptor mutant possessing a duplicated kinase domain

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.385

Authors: B H Ozer, G J Wiepz & P J Bertics

Inhibition of Akt signaling by the lignan matairesinol sensitizes prostate cancer cells to TRAIL-induced apoptosis

E Peuhu — 200-11-23

Inhibition of Akt signaling by the lignan matairesinol sensitizes prostate cancer cells to TRAIL-induced apoptosis

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.386

Authors: E Peuhu, A Rivero-Müller, H Stykki, E Torvaldson, T Holmbom, P Eklund, M Unkila, R Sjöholm & J E Eriksson

Transcriptional induction of MMP-10 by TGF-β, mediated by activation of MEF2A and downregulation of class IIa HDACs

F Ishikawa — 200-11-23

Transcriptional induction of MMP-10 by TGF-β, mediated by activation of MEF2A and downregulation of class IIa HDACs

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.387

Authors: F Ishikawa, H Miyoshi, K Nose & M Shibanuma

FLASH degradation in response to UV-C results in histone locus bodies disruption and cell-cycle arrest

L Bongiorno-Borbone — 200-11-16

FLASH degradation in response to UV-C results in histone locus bodies disruption and cell-cycle arrest

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.388

Authors: L Bongiorno-Borbone, A De Cola, D Barcaroli, R A Knight, C Di Ilio, G Melino & V De Laurenzi

Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

J Akech — 200-11-16

Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.389

Authors: J Akech, J J Wixted, K Bedard, M van der Deen, S Hussain, T A Guise, A J van Wijnen, J L Stein, L R Languino, D C Altieri, J Pratap, E Keller, G S Stein & J B Lian

Integrated genomic profiling identifies two distinct molecular subtypes with divergent outcome in neuroblastoma with loss of chromosome 11q

M Fischer — 200-11-09

Integrated genomic profiling identifies two distinct molecular subtypes with divergent outcome in neuroblastoma with loss of chromosome 11q

Oncogene advance online publication, November 9, 2009. doi:10.1038/onc.2009.390

Authors: M Fischer, T Bauer, A Oberthür, B Hero, J Theissen, M Ehrich, R Spitz, R Eils, F Westermann, B Brors, R König & F Berthold

Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer

N Khodarev — 200-11-16

Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.391

Authors: N Khodarev, R Ahmad, H Rajabi, S Pitroda, T Kufe, C McClary, M D Joshi, D MacDermed, R Weichselbaum & D Kufe

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

L Yang — 200-11-23

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.392

Authors: L Yang, G Xie, Q Fan & J Xie

Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling

S Guilmeau — 200-11-23

Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.393

Authors: S Guilmeau, M Flandez, J M Mariadason & L H Augenlicht

ATM and p53 are essential in the cell-cycle containment of DNA breaks during V(D)J recombination in vivo

M E Dujka — 200-11-16

ATM and p53 are essential in the cell-cycle containment of DNA breaks during V(D)J recombination in vivo

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.394

Authors: M E Dujka, N Puebla-Osorio, O Tavana, M Sang & C Zhu

miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors

M S Ostenfeld — 200-11-16

miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.395

Authors: M S Ostenfeld, J B Bramsen, P Lamy, S B Villadsen, N Fristrup, K D Sørensen, B Ulhøi, M Borre, J Kjems, L Dyrskjøt & T F Ørntoft

Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor

Y Lu — 200-11-16

Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.396

Authors: Y Lu, P Liu, M James, H G Vikis, H Liu, W Wen, A Franklin & M You

Mesenchymal–epithelial transition in epithelial response to injury: the role of Foxc2

C Hader — 200-11-23

Mesenchymal–epithelial transition in epithelial response to injury: the role of Foxc2

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.397

Authors: C Hader, A Marlier & L Cantley

Predicting the site of origin of tumors by a gene expression signature derived from normal tissues

E Staub — 200-11-16

Predicting the site of origin of tumors by a gene expression signature derived from normal tissues

Oncogene advance online publication, November 16, 2009. doi:10.1038/onc.2009.398

Authors: E Staub, H -J Buhr & J Gröne

Transcriptome profiling of a TGF-β-induced epithelial-to-mesenchymal transition reveals extracellular clusterin as a target for therapeutic antibodies

A E G Lenferink — 200-11-23

Transcriptome profiling of a TGF-β-induced epithelial-to-mesenchymal transition reveals extracellular clusterin as a target for therapeutic antibodies

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.399

Authors: A E G Lenferink, C Cantin, A Nantel, E Wang, Y Durocher, M Banville, B Paul-Roc, A Marcil, M R Wilson & M D O'Connor-McCourt

c-Jun activation is required for 4-hydroxytamoxifen-induced cell death in breast cancer cells

A Madeo — 200-11-23

c-Jun activation is required for 4-hydroxytamoxifen-induced cell death in breast cancer cells

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.400

Authors: A Madeo, M Vinciguerra, R Lappano, M Galgani, A Gasperi- Campani, M Maggiolini & A M Musti

Rictor is a novel target of p70 S6 kinase-1

C Treins — 200-11-23

Rictor is a novel target of p70 S6 kinase-1

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.401

Authors: C Treins, P H Warne, M A Magnuson, M Pende & J Downward

Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis

K Levanon — 200-11-23

Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.402

Authors: K Levanon, V Ng, H Y Piao, Yi Zhang, M C Chang, M H Roh, D W Kindelberger, M S Hirsch, C P Crum, J A Marto & R Drapkin

Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs

V Ramakrishnan — 200-11-23

Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.403

Authors: V Ramakrishnan, M Timm, J L Haug, T K Kimlinger, L E Wellik, T E Witzig, S V Rajkumar, A A Adjei & S Kumar

Embryoid body formation of human amniotic fluid stem cells depends on mTOR

A Valli — 200-11-23

Embryoid body formation of human amniotic fluid stem cells depends on mTOR

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.405

Authors: A Valli, M Rosner, C Fuchs, N Siegel, C E Bishop, H Dolznig, U Mädel, W Feichtinger, A Atala & M Hengstschläger

The microRNA network and tumor metastasis

H Zhang — 200-11-23

The microRNA network and tumor metastasis

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.406

Authors: H Zhang, Y Li & M Lai

Adenosine A1 receptor, a target and regulator of estrogen receptorα action, mediates the proliferative effects of estradiol in breast cancer

Z Lin — 200-11-23

Adenosine A1 receptor, a target and regulator of estrogen receptorα action, mediates the proliferative effects of estradiol in breast cancer

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.409

Authors: Z Lin, P Yin, S Reierstad, M O'Halloran, J S Coon V, E K Pearson, G M Mutlu & S E Bulun

Ras-induced invasion and metastasis are regulated by a leukotriene B4 receptor BLT2-linked pathway

E-Y Kim — 200-11-23

Ras-induced invasion and metastasis are regulated by a leukotriene B4 receptor BLT2-linked pathway

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.412

Authors: E-Y Kim, J-M Seo, K-J Cho & J-H Kim

Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer

B Y Ahn — 200-11-23

Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.413

Authors: B Y Ahn, D L N Trinh, L D Zajchowski, B Lee, A N Elwi & S -W Kim

Oncogenic and cell survival properties of the retinoic acid metabolizing enzyme, CYP26A1

M Osanai — 200-11-23

Oncogenic and cell survival properties of the retinoic acid metabolizing enzyme, CYP26A1

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.414

Authors: M Osanai, N Sawada & G -H Lee

A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy

Y Watanabe — 200-11-23

A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.415

Authors: Y Watanabe, T Kojima, S Kagawa, F Uno, Y Hashimoto, S Kyo, H Mizuguchi, N Tanaka, H Kawamura, D Ichimaru, Y Urata & T Fujiwara

Ezrin is a negative regulator of death receptor-induced apoptosis

W-C Kuo — 200-11-23

Ezrin is a negative regulator of death receptor-induced apoptosis

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.417

Authors: W-C Kuo, K-T Yang, S-L Hsieh & M-Z Lai

Fhit regulates invasion of lung tumor cells

A Joannes — 200-11-23

Fhit regulates invasion of lung tumor cells

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.418

Authors: A Joannes, A Bonnomet, S Bindels, M Polette, C Gilles, H Burlet, J Cutrona, J-M Zahm, P Birembaut & B Nawrocki-Raby

Differential epidermal growth factor receptor signaling regulates anchorage-independent growth by modulation of the PI3K/AKT pathway

J O Humtsoe — 200-11-23

Differential epidermal growth factor receptor signaling regulates anchorage-independent growth by modulation of the PI3K/AKT pathway

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.419

Authors: J O Humtsoe & R H Kramer

p53-dependent senescence delays Eμ-myc-induced B-cell lymphomagenesis

S M Post — 200-11-23

p53-dependent senescence delays Eμ-myc-induced B-cell lymphomagenesis

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.423

Authors: S M Post, A Quintás-Cardama, T Terzian, C Smith, C M Eischen & G Lozano

The tumor suppressor ING3 is degraded by SCFSkp2-mediated ubiquitin–proteasome system

G Chen — 200-11-23

The tumor suppressor ING3 is degraded by SCFSkp2-mediated ubiquitin–proteasome system

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.424

Authors: G Chen, Y Wang, M Garate, J Zhou & G Li

Caspase 2-mediated tumor suppression involves survivin gene silencing

M Guha — 200-11-23

Caspase 2-mediated tumor suppression involves survivin gene silencing

Oncogene advance online publication, November 23, 2009. doi:10.1038/onc.2009.428

Authors: M Guha, F Xia, C M Raskett & D C Altieri