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Isolation of an archaeon at the prokaryote–eukaryote interface
Isolation and characterization of an archaeon that is most closely related to eukaryotes reveals insights into how eukaryotes may have evolved from prokaryotes.
- Hiroyuki Imachi
- , Masaru K. Nobu
- & Ken Takai
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An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity
Bacteria and archaea use cyclic oligoadenylate molecules as part of the CRISPR system for antiviral defence; here, a family of viral enzymes that rapidly degrades cyclic oligoadenylates is identified and biochemically and structurally described.
- Januka S. Athukoralage
- , Stephen A. McMahon
- & Malcolm F. White
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Letter |
Accelerated growth in the absence of DNA replication origins
When all origins of replication are deleted from the archaeon Haloferax volcanii, homologous recombination is used to initiate DNA replication and the growth rate is accelerated.
- Michelle Hawkins
- , Sunir Malla
- & Thorsten Allers
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Structural basis of highly conserved ribosome recycling in eukaryotes and archaea
Cryo-electron-microscopy reconstructions of eukaryotic and archaeal ribosomes bound by ABCE1 and Pelota suggest a conserved mechanism for ribosome recycling.
- Thomas Becker
- , Sibylle Franckenberg
- & Roland Beckmann
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Letter |
Formate-driven growth coupled with H2 production
The oxidation of formate and water to bicarbonate and H2 is relatively common in microorganisms under anaerobic conditions. But can this reaction sustain growth in an isolated species? Here it is shown that several individual Thermococcus species can use formate oxidation for growth. Moreover, the biochemical basis of this ability is delineated.
- Yun Jae Kim
- , Hyun Sook Lee
- & Sung Gyun Kang