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Structural atlas of a human gut crassvirus
A cryo-electron microscopy reconstruction of the virus ΦcrAss001 provides insights into the functions of the viral gene products in capsid assembly and infection.
- Oliver W. Bayfield
- , Andrey N. Shkoporov
- & Alfred A. Antson
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Article |
Unified rhombic lip origins of group 3 and group 4 medulloblastoma
Multi-omic mapping shows that group 3 and group 4 medulloblastomas have a common, human-specific developmental origin in the cerebellar rhombic lip, providing a basis for their ambiguous molecular features and overlapping anatomical location, and for the difficulty of modelling these tumours in mice.
- Kyle S. Smith
- , Laure Bihannic
- & Paul A. Northcott
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Article |
A human liver cell atlas reveals heterogeneity and epithelial progenitors
Single-cell RNA sequencing of cells from healthy human liver, hepatocellular carcinoma and chimaeric mouse liver identifies subtypes of liver cells, epithelial progenitors and differences between healthy and diseased cells.
- Nadim Aizarani
- , Antonio Saviano
- & Dominic Grün
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Article |
DNA methylation-based classification of central nervous system tumours
An online approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups has been developed to help to improve current diagnostic standards.
- David Capper
- , David T. W. Jones
- & Stefan M. Pfister
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Article |
A single-cell survey of the small intestinal epithelium
Profiling of 53,193 individual epithelial cells from the mouse small intestine identifies previously unknown cell subtypes and corresponding gene markers, providing insight into gut homeostasis and response to pathogens.
- Adam L. Haber
- , Moshe Biton
- & Aviv Regev
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Letter |
Whole-brain serial-section electron microscopy in larval zebrafish
A complete larval zebrafish brain is examined and its myelinated axons reconstructed using serial-section electron microscopy, revealing remarkable symmetry and providing a valuable resource.
- David Grant Colburn Hildebrand
- , Marcelo Cicconet
- & Florian Engert
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Correspondence |
Call to register new species in ZooBank
- Gary Rosenberg
- , Frank-T. Krell
- & Richard Pyle
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Editorial |
The name game
After several years of wrangling, zoologists can now name new species online only.
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Research Highlights |
Botany: Final frontier of flowering plants
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Article |
Rise and fall of political complexity in island South-East Asia and the Pacific
- Thomas E. Currie
- , Simon J. Greenhill
- & Ruth Mace
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Opinion |
Time to automate identification
Taxonomists should work with specialists in pattern recognition, machine learning and artificial intelligence, say Norman MacLeod, Mark Benfield and Phil Culverhouse — more accuracy and less drudgery will result.
- Norman MacLeod
- , Mark Benfield
- & Phil Culverhouse
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Research Highlights |
Plant taxonomy: Flower and be counted
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News |
Linnaeus meets the Internet
Test case for electronic publication of new species names breaks with over 200 years of history.
- Daniel Cressey
Evolution of neuronal cell classes and types in the vertebrate retina
English not Latin in botanical reports