Coeliac disease articles within Nature

Featured

• Article | 12 February 2020

  IL-15, gluten and HLA-DQ8 drive tissue destruction in coeliac disease

  An HLA- and gluten-dependent mouse model of coeliac disease with villous atrophy provides evidence for the cooperative role of IL-15 and gluten-specific CD4⁺ T cells in licensing the full activation of cytotoxic T cells that are necessary for inducing epithelial damage.

  • Valérie Abadie
  • , Sangman M. Kim
  •  & Bana Jabri

• News & Views | 09 March 2011

  Context is key in the gut

  The vitamin-A metabolite retinoic acid normally favours immune tolerance in the gut. But in coeliac disease — an intestinal inflammatory disorder due to adverse reactivity to a dietary protein — it may do just the opposite. See Letter p.220

  • Craig L. Maynard
  •  & Casey T. Weaver

• News Explainer | 14 January 2011

  Is breast not best for babies?

  New evidence contradicts World Health Organization breastfeeding advice.

  • Natasha Gilbert