Featured
-
-
Article |
Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis
Blockade of the C5a–C5aR1 axis using anti-C5aR1 monoclonal antibodies prevented inflammation associated with COVID-19.
- Julien Carvelli
- , Olivier Demaria
- & Eric Vivier
-
Article |
Complement genes contribute sex-biased vulnerability in diverse disorders
Sexual dimorphism in genetic vulnerability to schizophrenia, systemic lupus erythematosus and Sjögren’s syndrome is linked to differential protein abundance from alleles of complement component 4.
- Nolan Kamitaki
- , Aswin Sekar
- & Steven A. McCarroll
-
Letter |
Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease
Complement-activating glycosylceramide-specific autoantibodies drive a self-propagating cycle of glycosylceramide accumulation and inflammation in Gaucher disease.
- Manoj K. Pandey
- , Thomas A. Burrow
- & Gregory A. Grabowski