Featured
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Article |
Codon influence on protein expression in E. coli correlates with mRNA levels
In-depth analyses of protein expression studies are used to derive a new codon-influence metric that correlates with global protein levels, mRNA levels and mRNA lifetimes in vivo, indicating tight coupling between translation efficiency and mRNA stability; genes redesigned based on these analyses consistently yield high protein expression levels both in vivo and in vitro.
- Grégory Boël
- , Reka Letso
- & John F. Hunt
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News |
India to cut out animal dissection
University funding body recommends a phase-out, but gives no final date.
- Priya Shetty
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Article |
A sensing array of radically coupled genetic ‘biopixels’
Thousands of quorum-sensing Escherichia coli colonies are synchronized over centimetres using redox signalling to create ‘biopixels’ that can sense trace amounts of arsenic in water.
- Arthur Prindle
- , Phillip Samayoa
- & Jeff Hasty
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Books & Arts |
Cosmology: The untestable multiverse
George Ellis reminds us that Brian Greene's beguiling book on parallel worlds is more theory than fact.
- George Ellis
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News |
Germans cook up liver project
Biologists join physicists in a bid to map the workings of the human organ at all scales.
- Alison Abbott
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News & Views |
Ocean biomes blended
The ratio of nutrient elements in marine subsurface waters is much the same everywhere, even though biogeochemically distinct ocean biomes exist. A modelling study that includes mixing solves this conundrum. See Article p.550
- Raymond N. Sambrotto
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News & Views |
Closing in on evaders
A simple model highlights the pros and cons of chasing — and escaping — in groups. It shows that, for a given number of prey animals, an optimal number of predators exists that maximizes the success of the catch.
- Tamás Vicsek
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News & Views |
Wider role for airborne chlorine
Unexpected chlorine chemistry in the lowest part of the atmosphere can affect the cycling of nitrogen oxides and the production of ozone, and reduce the lifetime of the greenhouse gas methane.
- Roland von Glasow