Dynamic networks articles within Nature

Featured

• Article | 30 November 2015

  ∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis

  A new deep proteomic analysis method is used to identify proteins that interact with wild-type cystic fibrosis transmembrane conductance regulator (CFTR) and its mutant version that is the major cause of cystic fibrosis.

  • Sandra Pankow
  • , Casimir Bamberger
  •  & John R. Yates III

• Article | 10 July 2013

  Temporal regulation of EGF signalling networks by the scaffold protein Shc1

  The Shc1 scaffold mediates a switch in the signaling output of the epidermal growth factor receptor tyrosine kinase over time through recruitment of successive waves of proteins with distinct biological functions.

  • Yong Zheng
  • , Cunjie Zhang
  •  & Tony Pawson