Gene duplication articles within Nature

Featured

• Letter | 05 October 2016

  Formation of new chromatin domains determines pathogenicity of genomic duplications

  Genomic duplications in the SOX9 region are associated with human disease phenotypes; a study using human cells and mouse models reveals that the duplications can cause the formation of new higher-order chromatin structures called topologically associated domains (TADs) thereby resulting in changes in gene expression.

  • Martin Franke
  • , Daniel M. Ibrahim
  •  & Stefan Mundlos

• Research Highlights | 09 May 2012

  Gene duplication for bigger brains

• News | 03 May 2012

  Human brain shaped by duplicate genes

  Multiple copies of a gene may have boosted the computational power of our ancestors' brains.

  • Ewen Callaway

• Research Highlights | 24 February 2010

  Genetics: Male regulator switched