Research Highlights |
Featured
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Letter |
Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans
Biochemical and structural analysis of the drug transporter P-glycoprotein in Caenorhabditis elegans at a resolution of 3.4 angstroms is used to generate a homology model of the human protein and supports a picture in which P-glycoprotein uses the energy from ATP hydrolysis to expel lipophilic molecules from the inner leaflet of the cell membrane.
- Mi Sun Jin
- , Michael L. Oldham
- & Jue Chen
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Letter |
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
- Kerstin Berer
- , Marsilius Mues
- & Gurumoorthy Krishnamoorthy
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Research Highlights |
Chemical biology: With added sugar